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Open AccessJournal ArticleDOI

Sudden death in asthma.

J R Bateman, +1 more
- 01 Feb 1979 - 
- Vol. 34, Iss: 1, pp 40-44
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TLDR
Two deaths after sudden severe asthma attacks in young people are reported from a clinic set up to identify and manage "at risk" patients, despite frequent visits at which recommendations made by previous studies were implemented.
Abstract
Two deaths after sudden severe asthma attacks in young people are reported from a clinic set up to identify and manage "at risk" patients. These deaths occurred despite frequent visits at which recommendations made by previous studies were implemented. The risk factors and management of such episodes have been reviewed. Precautions taken proved inadequate due to the severe, abrupt nature of the attacks, failure of the patients' immediate treatment, and delay in reaching hospital. Consideration should be given to the self-administration of subcutaneous adrenaline or specific beta-agonists, the provision of a detailed medical card, and free access to the nearest hospital in such cases.

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Citations
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Journal ArticleDOI

Comparison of normal and asthmatic circadian rhythms in peak expiratory flow rate.

M R Hetzel, +1 more
- 01 Oct 1980 - 
TL;DR: Nocturnal asthma probably represents an exaggeration of a normal circadian rhythm in airway calibre in normals and asthmatics and the amplitude of the PEFR rhythm is an index of bronchial lability and is thus valuable in monitoring asthma patients.
Journal ArticleDOI

The new NHS.

D Plamping
- 30 Mar 1991 - 
TL;DR: The NHS revieworrectly challenged two assumptions on which public service organisations have been based, and recent experience in the United States suggests that having competing providers and powerful, discriminating purchasers may reduce costs without compromising outcomes in acute care.
Journal ArticleDOI

Evaluation of peak flow and symptoms only self management plans for control of asthma in general practice.

TL;DR: The peak flow meter was not the crucial ingredient in the improved illness of the two groups and teaching patients the importance of their symptoms and the appropriate action to take when their asthma deteriorates is the key to effective management of asthma.
Journal ArticleDOI

A self management plan in the treatment of adult asthma.

TL;DR: Routine measurement of PEF in association with a self management plan appears to be effective in reducing symptoms of asthma and improving lung function, with a substantial improvement in both subjective and objective measurements of asthma severity.
Journal ArticleDOI

Chronobiology, drug delivery, and chronotherapeutics.

TL;DR: Next generation drug-delivery systems must be configurable so they respond to sensitive biomarkers of disease activity that often vary in time as periodic (circadian rhythmic) and non-periodic patterns to release medication to targeted tissue(s) on a real time as needed basis, and are cost-effective.
References
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Journal ArticleDOI

Rise and fall of asthma mortality in england and wales in relation to use of pressurised aerosols

W.H.W. Inman, +1 more
- 09 Aug 1969 - 
TL;DR: It is concluded that the excess deaths, which were estimated to have numbered more than 3500 in the period 1961-67, were likely to have been the result of over use of pressurised aerosols and that the subsequent decline in mortality has resulted from a greater awareness by doctors and patients of the dangers of overuse.
Journal ArticleDOI

Asthma: analysis of sudden deaths and ventilatory arrests in hospital.

M R Hetzel, +2 more
- 26 Mar 1977 - 
TL;DR: The risk of sudden death could not be related to the severity of the attack but it did correlate with the presence of excessive diurnal variation in peak expiratory flow rate (PEFR).
Journal ArticleDOI

A survey of asthma mortality in patients between ages 35 and 64 in the Greater London hospitals in 1971.

G M Cochrane, +1 more
- 01 Jun 1975 - 
TL;DR: Examination of death certificates from all patients aged 35-64 years who were recorded as dying from asthma in Greater London Council hospitals in 1971 found that 15 deaths occurred outside hospital and another two patients died in hospital having been admitted in a stable state.
Journal ArticleDOI

Asthma deaths in Cardiff 1963-74: 90 deaths outside hospital.

J B MacDonald, +2 more
- 19 Jun 1976 - 
TL;DR: These deaths might be prevented by better patient education, a self-admission service for selected asthmatics, and by doctors using objective measurements of severity of asthma for the control of treatment.