Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal replacement therapy
Shahid M. Chandna,Maria Da Silva-Gane,Catherine Marshall,Paul Warwicker,Roger Greenwood,Ken Farrington +5 more
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TLDR
In patients aged > 75 years with high extra-renal comorbidity, the survival advantage conferred by RRT over CM is likely to be small and age >75 years and female gender independently predicted better survival.Abstract:
© The Author 2010. Published by Oxford University Press on behalf of the ERA-EDTA. All rights reserved. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly citedread more
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Journal ArticleDOI
Management of chronic kidney disease in the elderly.
B. L. Ng,M. Anpalahan +1 more
TL;DR: The current evidence is reviewed with a view to providing a framework for diagnosing and managing CKD in the elderly and special references are made to age‐related physiological changes in the renal system, assessment of renal function, and management of metabolic complications and end‐stage renal disease.
Dissertation
Psychosocial distress in older patients with advanced chronic kidney disease
TL;DR: A simple tool, the Distress Thermometer (DT), is developed to identify distress associated with unmet need in cancer patients, however it has not yet been validated for use in renal patients.
Journal ArticleDOI
Low performance of prognostic tools for predicting death before dialysis in older patients with advanced CKD.
Julien Prouvot,Emilie Pambrun,Valéry Antoine,Cécile Couchoud,Cécile Vigneau,Sophie Roche,Maud Francois,Christophe Mariat,Daniela Babici,C. Prelipcean,Olivier Moranne,Pspa Study Investigators +11 more
TL;DR: In this article, the authors evaluated the existing risk scores for predicting death before dialysis start, identified via an in-depth review, in a cohort of elderly patients with advanced CKD.
Journal ArticleDOI
The Very Old on Hemodialysis: 8 Years' Experience in a Single Unit
Boris Zingerman,Asher Korzets,Yaacov Ori,Michal Herman-Edelstein,Benaya Rozen-Zvi,Uzi Gafter,Avry Chagnac +6 more
TL;DR: Very elderly patients can be hemodialyzed with cautious optimism, according to a single-center retrospective analysis carried out on patients >84 years of age who started chronic dialysis between 2004 and 2012.
References
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Functional Status of Elderly Adults before and after Initiation of Dialysis
Manjula Kurella Tamura,Kenneth E. Covinsky,Glenn M. Chertow,Kristine Yaffe,C. Seth Landefeld,Charles E. McCulloch +5 more
TL;DR: The initiation of dialysis is associated with a substantial and sustained decline in functional status among nursing home residents with ESRD, and this decline was independent of age, sex, race, and functional-status trajectory before the initiation ofdialysis.
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Gender differences in insulin resistance, body composition, and energy balance.
Eliza B. Geer,Wei Shen +1 more
TL;DR: Greater amounts of visceral and hepatic adipose tissue, in conjunction with the lack of a possible protective effect of estrogen, may be related to higher insulin resistance in men compared with women.
Journal ArticleDOI
Dialysis or not? A comparative survival study of patients over 75 years with chronic kidney disease stage 5
Fliss E M Murtagh,James E. Marsh,Paul Donohoe,Nasirul J. Ekbal,Neil S. Sheerin,Fiona E. Harris +5 more
TL;DR: In CKD stage 5 patients over 75 years, who receive specialist nephrological care early, and who follow a planned management pathway, the survival advantage of dialysis is substantially reduced by comorbidity and ischaemic heart disease in particular.
Journal ArticleDOI
Is Maximum Conservative Management an Equivalent Treatment Option to Dialysis for Elderly Patients with Significant Comorbid Disease
TL;DR: Dialysis prolongs survival for elderly patients who have ESRD with significant comorbidity by approximately 2 yr; however, patients who choose MCM can survive a substantial length of time, achieving similar numbers of hospital-free days to patients who choice hemodialysis.
Journal ArticleDOI
Octogenarians Reaching End-Stage Renal Disease: Cohort Study of Decision-Making and Clinical Outcomes
Dominique Joly,Dany Anglicheau,Corinne Alberti,Anh-Thu Nguyen,Malik Touam,Jean-Pierre Grünfeld,Paul Jungers +6 more
TL;DR: It is concluded that beside a patient's individual refusal, late referral, social isolation, low functional capacity, and diabetes may have oriented medical decision toward withholding dialysis in a significant proportion of pre-ESRD octogenarians.