Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal replacement therapy
Shahid M. Chandna,Maria Da Silva-Gane,Catherine Marshall,Paul Warwicker,Roger Greenwood,Ken Farrington +5 more
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TLDR
In patients aged > 75 years with high extra-renal comorbidity, the survival advantage conferred by RRT over CM is likely to be small and age >75 years and female gender independently predicted better survival.Abstract:
© The Author 2010. Published by Oxford University Press on behalf of the ERA-EDTA. All rights reserved. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly citedread more
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Decision-making for people with dementia and advanced kidney disease: a secondary qualitative analysis of interviews from the Conservative Kidney Management Assessment of Practice Patterns Study.
Jemima Scott,Amanda Owen-Smith,Sarah Tonkin-Crine,Hugh C. Rayner,Paul Roderick,Ikumi Okamoto,Geraldine Leydon,Fergus Caskey,Shona Methven +8 more
TL;DR: In this article, the authors explored dialysis decision-making for adults who lack capacity due to cognitive impairment, a common and under-recognised condition in those with advanced chronic kidney disease (CKD).
Journal ArticleDOI
Survival of Older Patients With Advanced CKD Managed Without Dialysis: A Narrative Review
Angela Chou,Kelly Li +1 more
TL;DR: In this paper , a narrative review is presented to summarize the existing studies on the survival of older patients with stage 4 or 5 chronic kidney disease managed with or without dialysis and to evaluate the factors that may influence mortality in an effort to assist clinicians with shared decision making.
Journal ArticleDOI
Incorporating the Clinical Frailty Scale into routine outpatient nephrology practice: an observational study of feasibility and associations.
Anuttara Panchali Kumarasinghe,Anuttara Panchali Kumarasinghe,Aron Chakera,Aron Chakera,Kien Chan,Sharan Dogra,Sally Broers,Sean Maher,Charles A. Inderjeeth,Charles A. Inderjeeth,Angela Jacques +10 more
TL;DR: Frailty assessment via CFS was feasible in outpatient practice, when integrated into routine clinical assessment in a dedicated clinic, and appears associated with increased planned Conservative Management of ESKD.
Journal ArticleDOI
The Factors Affecting Survival in Geriatric Hemodialysis Patients.
TL;DR: It is revealed that comorbidities and low performance status at the onset of dialysis had shortened the survival time in the geriatric hemodialysis patient group.
Journal ArticleDOI
Variability in the incidence of renal replacement therapy over time in Western industrialized countries: A retrospective registry analysis.
Vicky De Meyer,Daniel Abramowicz,Johan De Meester,Frederic Collart,Jean-Louis Bosmans,Wilfried Cools,Karl Martin Wissing +6 more
TL;DR: Different incidence rates of RRT between industrialized countries worldwide were confirmed, with countries with the highest overall incidence rates also had the highest incidence rates in the oldest age categories.
References
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Functional Status of Elderly Adults before and after Initiation of Dialysis
Manjula Kurella Tamura,Kenneth E. Covinsky,Glenn M. Chertow,Kristine Yaffe,C. Seth Landefeld,Charles E. McCulloch +5 more
TL;DR: The initiation of dialysis is associated with a substantial and sustained decline in functional status among nursing home residents with ESRD, and this decline was independent of age, sex, race, and functional-status trajectory before the initiation ofdialysis.
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Gender differences in insulin resistance, body composition, and energy balance.
Eliza B. Geer,Wei Shen +1 more
TL;DR: Greater amounts of visceral and hepatic adipose tissue, in conjunction with the lack of a possible protective effect of estrogen, may be related to higher insulin resistance in men compared with women.
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Dialysis or not? A comparative survival study of patients over 75 years with chronic kidney disease stage 5
Fliss E M Murtagh,James E. Marsh,Paul Donohoe,Nasirul J. Ekbal,Neil S. Sheerin,Fiona E. Harris +5 more
TL;DR: In CKD stage 5 patients over 75 years, who receive specialist nephrological care early, and who follow a planned management pathway, the survival advantage of dialysis is substantially reduced by comorbidity and ischaemic heart disease in particular.
Journal ArticleDOI
Is Maximum Conservative Management an Equivalent Treatment Option to Dialysis for Elderly Patients with Significant Comorbid Disease
TL;DR: Dialysis prolongs survival for elderly patients who have ESRD with significant comorbidity by approximately 2 yr; however, patients who choose MCM can survive a substantial length of time, achieving similar numbers of hospital-free days to patients who choice hemodialysis.
Journal ArticleDOI
Octogenarians Reaching End-Stage Renal Disease: Cohort Study of Decision-Making and Clinical Outcomes
Dominique Joly,Dany Anglicheau,Corinne Alberti,Anh-Thu Nguyen,Malik Touam,Jean-Pierre Grünfeld,Paul Jungers +6 more
TL;DR: It is concluded that beside a patient's individual refusal, late referral, social isolation, low functional capacity, and diabetes may have oriented medical decision toward withholding dialysis in a significant proportion of pre-ESRD octogenarians.