Systolic and diastolic abnormalities of the left ventricle in coronary artery disease. Studies in patients with little or no enlargement of ventricular volume.
TLDR
It is concluded that patients without significant increase in left ventricular enddiastolic volume had abnormalities of diastolic compliance and contractile performance.Abstract:
Left ventricular volume and circumference were calculated from cineangiocardiograms at 60 frames/sec in 15 patients with arteriographically proven coronary artery disease (CAD) and five control subjects. The patients with CAD had no mitral regurgitation and had an average end-diastolic volume equivalent to that reported by others in normal subjects and to that of the control group. The average end-diastolic pressure was higher in CAD and was often abnormal, despite lack of increase in enddiastolic volume. The ejection was lower in the CAD group as was the extent of circumferential fiber shortening. Maximal and mean rates of fiber shortening correlated positively with ejection fraction and were low in some individuals with CAD. We conclude that our patients without significant increase in left ventricular enddiastolic volume had abnormalities of diastolic compliance and contractile performance.read more
Citations
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Assessment of diastolic function of the heart: background and current applications of Doppler echocardiography. Part II. Clinical studies.
TL;DR: An interpretation of the mitral valve, tricuspid valve, and systemic and pulmonary venous inflow velocities in the normal patient and in various disease states is provided.
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Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects.
Anand Kumar,Ramon Anel,Eugene Bunnell,Kalim Habet,Sergio Zanotti,Stephanie Marshall,Alex Neumann,Amjad Ali,Mary Cheang,Clifford J. Kavinsky,Joseph E. Parrillo +10 more
TL;DR: Normal healthy volunteers demonstrate a lack of correlation between initial central venous pressure/pulmonary artery occlusion pressure and both end-diastolic ventricular volume indexes and stroke volume index, suggesting a more universal phenomenon that includes normal subjects.
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Impaired left ventricular diastolic filling in patients with coronary artery disease: assessment with radionuclide angiography.
Robert O. Bonow,Stephen L. Bacharach,Michael V. Green,Kenneth M. Kent,Douglas R. Rosing,Lewis C. Lipson,Martin B. Leon,S E Epstein +7 more
TL;DR: LV diastolic filling, evaluated noninvasively by radionuclide angiography, is abnormal in a high percentage of patients with CAD at rest independent of LV systolic function or previous myocardial infarction.
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Determination of parameters of left ventricular diastolic filling with pulsed Doppler echocardiography: comparison with cineangiography.
TL;DR: To determine the relationship between Doppler-derived flow velocity through the mitral anulus and angiographic parameters of left ventricular filling, 30 patients were studied by two-dimensional echocardiography combined with pulsed Dopplers echOCardiography followed within 1 hr byleft ventricular angiography.
Journal ArticleDOI
Diastolic Properties of the Left Ventricle
TL;DR: Left ventricular pressure and volume during diastole reflect the interaction of ventricular elastic, viscous, and inertial properties, and the completeness of myocardial relazation, and may be impaired in the acutely ischemic ventricle.
References
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Estimation of Left Ventricular Volume by One-Plane Cineangiography
TL;DR: One-plane cineangiographic measurement of left ventricular volume uses angiocardiograms taken in the right anterior oblique view, which means that effects of drugs and other interventions can be studied by the informative techniques of semi-continuous volume measurement and pressure-volume analysis.
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Implications of left ventricular asynergy
Michael V. Herman,Richard Gorlin +1 more
TL;DR: Ventricular asynergy represents a dynamic abnormality appreciated only in life as a derangement of the integrated function of the left ventricle and represents an important cause of cardiac failure.
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Quantitative angiocardiography. I. The normal left ventricle in man.
TL;DR: The ventricular volumes did not correlate well with age, sex, body surface area, or weight, but correlated in a negative manner with heart rate, and there was a significant difference between left ventricular wall thickness and mass in normal men and women.
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Contractile State of the Left Ventricle in Man: Instantaneous Tension-Velocity-Length Relations in Patients With And Without Disease of the Left Ventricular Myocardium
TL;DR: The contractile state of the left ventricle in man was analyzed by correlating left ventricular dimensional changes during contraction determined from cineangiograms, with simultaneous measurements of LV pressure and the time course of LV wall tension (stress).