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Technological aspects and potential applications of (ultra) high-pressure homogenisation

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TLDR
A review of high-pressure homogenization can be found in this article, where the authors discuss piston-gap type high pressure homogenisers equipped with specially designed HP-valves.
Abstract
The present review concerns homogenisation processing, and more particularly high-pressure homogenisation. Recent developments in high-pressure technology and the design of new homogenisation valves able to withstand pressures up to 350–400 MPa have indeed opened new opportunities to homogenisation processing in the dairy, pharmaceutical and cosmetic industries. Homogenisers equipped with high-pressure valves or interaction chambers of different designs, and consequently different flow characteristics (laminar or turbulent flow, cavitation, impingement on solid walls, fluid jet collision) are available. The present review will more particularly concern piston-gap type high-pressure homogenisers equipped with specially designed HP-valves able to reach 300–400 MPa for ultra-high-pressure homogenisation (UHPH). An overview of some recent UHPH studies will be summarised in the following sections including UHPH-induced microbial inactivation, characteristics of submicron emulsions and UHPH-induced protein structural changes and functionality.

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Citations
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References
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Journal ArticleDOI

Formation and stability of nano-emulsions

TL;DR: This review describes the principles of formation and stability of nano-emulsions, namely high energy emulsification (using homogenisers), low energy emulsion preparation, and the principle of the phase inversion temperature (PIT), and the role of the adsorbed layer thickness.
Journal ArticleDOI

Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation

TL;DR: The physical background of the diminution process, effects of production parameters (power density, number of homogenisation cycles) on crystal size, clinical batch production and scaling up of the production are presented.
Journal ArticleDOI

Re-coalescence of emulsion droplets during high-energy emulsification

TL;DR: In this article, a review highlights re-coalescence of new droplets during high-energy emulsification along with some common and important emulsion techniques and different factors affecting emulsion droplet size.
Journal ArticleDOI

Fluorescence study of the curcumin-casein micelle complexation and its application as a drug nanocarrier to cancer cells.

TL;DR: Fluorescence quenching showed that curcumin molecules quench the intrinsic fluorescence of caseins upon binding, and the utility of CMs as carriers ofCurcumin was evaluated by using in vitro cultured HeLa cells.
Journal ArticleDOI

Effect of high-pressure homogenization on droplet size distributions and rheological properties of model oil-in-water emulsions

TL;DR: A new ultra high-pressure homogenizer (STANSTED, UK) going up to 350 MPa was used to realize very fine oil-in-water emulsions.
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Trending Questions (1)
How does high pressure homogenisation affect the protein content in dry substances?

High-pressure homogenisation can induce protein structural changes and affect functionality in dry substances, as discussed in the paper.