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Open AccessJournal ArticleDOI

“The Adipocyte: A Multifunctional Cell”

Bruce M. Spiegelman, +1 more
- 01 Dec 2006 - 
- Vol. 4, Iss: 6, pp 425-427
TLDR
The beautiful Thorskog Castle just north of Göteborg on the Swedish west coast was the venue for the 134th Nobel Symposium, entitled "The Adipocyte: A Multifunctional Cell."
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This article is published in Cell Metabolism.The article was published on 2006-12-01 and is currently open access. It has received 23 citations till now.

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Adipokines: a review of biological and analytical principles and an update in dogs, cats, and horses

M. Judith Radin, +2 more
- 01 Jun 2009 - 
TL;DR: The function and regulation of some better-characterized adipokines are summarized and some domestic species in which rates of obesity and obesity-related disorders are increasing, such as the dog, cat, and horse are reviewed.
Journal ArticleDOI

Obesity and diabetes: the link between adipose tissue dysfunction and glucose homeostasis.

Monise Viana Abranches, +3 more
- 01 Dec 2015 - 
TL;DR: It is demonstrated how glucose homeostasis is changed by AT dysfunction, which enables performing nutritional intervention strategies with the goal of preventing T2DM.
Journal ArticleDOI

Metabolic Actions of Hypothalamic SIRT1

Roberto Coppari, +1 more
- 01 Apr 2012 - 
TL;DR: Findings indicate that a nicotinamide adenine dinucleotide (NAD(+))-dependent protein deacetylase (namely SIRT1) expressed by hypothalamic neurons is crucial for mounting responses against diet-induced obesity and type 2 diabetes mellitus (T2DM), and the repercussions of these findings will be discussed.
Journal ArticleDOI

Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype

Xianglan Liu, +6 more
- 01 Jan 2014 - 
TL;DR: A family of novel engineered hybrid capsid serotypes (Rec1~4) recombinant adeno-associated viral (AAV) vectors in comparison with natural serotypes AAV1, AAV8, and AAV9 led to widespread transduction in both brown fat and white fat with the highest efficiency among the seven serotypes tested.
Journal ArticleDOI

Peroxisome proliferator-activated receptor: effects on nutritional homeostasis, obesity and diabetes mellitus

M. Viana Abranches, +2 more
- 01 Mar 2011 - 
TL;DR: The present review aims to understand the relationship between the diet, the PPARs and the control of the blood glucose and body weight, since the understanding about the mechanisms by which these receptors act may benefit the development of the strategies aiming at prevention and elaboration of therapeutics actions which are more effective for the treatment of obesity and diabetes.