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Journal ArticleDOI

The Contraceptive Vaginal Ring

Jill Edwardson, +1 more
- 01 Mar 2010 - 
- Vol. 28, Iss: 2, pp 133-139
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TLDR
The contraceptive vaginal ring offers effective contraception that is self-administered, requires less frequent dosing than many other forms of contraception, and provides low doses of hormones.
Abstract
The contraceptive vaginal ring offers effective contraception that is self-administered, requires less frequent dosing than many other forms of contraception, and provides low doses of hormones. NuvaRing (Organon, Oss, The Netherlands), the only contraceptive vaginal ring approved for use in the United States, contains etonogestrel and ethinyl estradiol. It is inserted into the vagina for 3 weeks, followed by a 1-week ring-free period, and works by inhibiting ovulation. Most women note a beneficial effect on bleeding profiles and are satisfied with NuvaRing. Commonly reported adverse events include vaginitis, leukorrhea, headaches, and device-related events such as discomfort. Serious adverse events are rare. In Chile and Peru, progesterone-only vaginal contraceptive rings are available for nursing women. Studies are ongoing examining new formulations of vaginal contraceptive rings.

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Journal ArticleDOI

Contraception for adolescents.

Mary A. Ott, +1 more
- 01 Oct 2014 - 
TL;DR: This technical report provides an evidence base for the accompanying policy statement and addresses key aspects of adolescent contraceptive use, including the following: sexual history taking, confidentiality, and counseling; adolescent data on the use and side effects of newer contraceptive methods; new data on older contraceptives methods; and evidence supporting the use of contraceptives in adolescent patients with complex medical conditions.
Journal ArticleDOI

Review of the combined contraceptive vaginal ring, NuvaRing.

TL;DR: Good results with respect to contraceptive efficacy, cycle control, tolerability, and acceptability as achieved with NuvaRing in the large non-comparative registration studies were confirmed in the RCTs comparing Nuva ring with different COCs.
Journal ArticleDOI

Pharmacokinetics of a Multipurpose Pod-Intravaginal Ring Simultaneously Delivering Five Drugs in an Ovine Model

TL;DR: This proof-of-principle study demonstrates that pod IVRs can deliver three ARVs from different mechanistic classes and a progestin-estrogen combination over the wide range needed for putative preventative efficacy.
Journal ArticleDOI

Novel multipurpose pod-intravaginal ring for the prevention of HIV, HSV, and unintended pregnancy: Pharmacokinetic evaluation in a macaque model

TL;DR: This proof of principle study demonstrates that MPT-pod IVRs could serve as a potent biomedical prevention tool to protect women’s sexual and reproductive health and may increase adherence to HIV PrEP even among younger high-risk populations.
Journal ArticleDOI

Managing women with gestational diabetes mellitus in the postnatal period

TL;DR: Current recommendations for managing women with GDM in the postnatal period are discussed, with particular attention to postpartum diabetes screening, prevention of future glucose intolerance and family planning.
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