Sean Kennedy

TL;DR: The authors' classifications based on variation in the gut microbiome identify subsets of individuals in the general white adult population who may be at increased risk of progressing to adiposity-associated co-morbidities.

TL;DR: The gut microbiome in liver cirrhosis is characterized by comparing 98 patients and 83 healthy control individuals and on the basis of only 15 biomarkers, a highly accurate patient discrimination index is created and validated on an independent cohort, suggesting microbiota-targeted biomarkers may be a powerful tool for diagnosis of different diseases.

TL;DR: Diet-induced weight-loss and weight-stabilization interventions in a study sample of obese and overweight individuals are conducted and it is reported that individuals with reduced microbial gene richness present more pronounced dys-metabolism and low-grade inflammation.

TL;DR: In this paper, the authors evaluated the association between faecal A. muciniphila abundance and microbial gene richness after calorie restriction (CR) in overweight and obese adults.

TL;DR: This work presents a method, based on binning co-abundant genes across a series of metagenomic samples, that enables comprehensive discovery of new microbial organisms, viruses and co-inherited genetic entities and aids assembly of microbial genomes without the need for reference sequences.