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Open AccessJournal ArticleDOI

The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study

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TLDR
The evidence challenges the increasing trend for more total hip replacements and total knee replacements to be done in the younger patient group, and these data should be offered to patients as part of the shared decision making process.
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This article is published in The Lancet.The article was published on 2017-04-08 and is currently open access. It has received 489 citations till now. The article focuses on the topics: Hip surgery & Knee replacement.

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Citations
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Osteoarthritis year in review 2019: epidemiology and therapy.

TL;DR: While waiting for new treatment modalities to appear joint replacement is an effective alternative; new data have become available on how long they might last, suggesting further studies and reconsideration of currently used guidelines are warranted.
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Projections and Epidemiology of Revision Hip and Knee Arthroplasty in the United States to 2030

TL;DR: The incidence of rTHA/rTKA is projected to increase, particularly in young patients and for infection, which should encourage institutions to generate revision-specific protocols to promote safe pathways for cost-effective care that is commensurate with current value-based health care trends.
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Wnt signaling: a promising target for osteoarthritis therapy.

TL;DR: This review summarizes the role and mechanism of Wnt signaling and related molecules in regulating OA progression, with a view to accelerating the translation of such evidence into the development of strategies for OA treatment, particularly with respect to potential applications of molecules targeting the Wnt signalling pathway.
References
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Journal ArticleDOI

The operation of the century: total hip replacement

TL;DR: Universal economic constraints in healthcare services dictate that further developments in total hip replacement will be governed by their cost-effectiveness, and computer-assisted surgery will contribute to reproducible and accurate placement of implants.
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Data Resource Profile: Clinical Practice Research Datalink (CPRD)

TL;DR: The CPRD primary care database is a rich source of health data for research, including data on demographics, symptoms, tests, diagnoses, therapies, health-related behaviours and referrals to secondary care, but researchers must be aware of the complexity of routinely collected electronic health records.
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Future young patient demand for primary and revision joint replacement: national projections from 2010 to 2030.

TL;DR: In this paper, the authors developed projections for demand of total joint replacement (TJR) surgery in young patients (< 65 years old) in the United States, using the Nationwide Inpatient Sample (NIS) between 1993 and 2006.
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Lifetime risk of symptomatic knee osteoarthritis

TL;DR: Nearly half of the adults in Johnston County will develop symptomatic knee OA by age 85 years, with lifetime risk highest among obese persons, which underscores the immediate need for greater use of clinical and public health interventions, especially those that address weight loss and self-management.
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All cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort study.

TL;DR: Patients with osteoarthritis are at higher risk of death compared with the general population, and history of diabetes, cancer, or cardiovascular disease and the presence of walking disability are major risk factors.
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