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Journal ArticleDOI

The glyoxylate cycle and the conversion of triglycerides to carbohydrates in developing eggs of Ascaris lumbricoides

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TLDR
The glyoxylate cycle and the conversion of 4-carbon dicarboxylic acids to trehalose and glycogen account for the unique synthesis of carbohydrate from higher fatty acids.
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This article is published in Comparative Biochemistry and Physiology.The article was published on 1970-08-01. It has received 90 citations till now. The article focuses on the topics: Glyoxylate cycle & Isocitrate lyase.

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Itaconate, an isocitrate lyase-directed inhibitor in Pseudomonas indigofera.

B A McFadden, +1 more
TL;DR: Itaconate, a potent inhibitor of isocitrate lyase, abolished growth of P. indigofera on ethanol at concentrations that had little effect upon growth on glucose, suggesting that itaconate selectively inhibits and reduces the specific activity of isOCitrate Lyase.
Journal ArticleDOI

The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans.

TL;DR: Results suggest that genes that regulate metabolic activity may play central roles in longevity and senescence in aging Caenorhabditis elegans.
Journal ArticleDOI

Developmental regulation of energy metabolism in Caenorhabditis elegans.

TL;DR: It is concluded that metabolism is regulated during C. elegans larval development, with a major transition apparent after the L1 stage, but this transition does not occur in larvae destined to form dauer larvae.
Journal ArticleDOI

Biochemical adaptation and loss of genetic capacity in helminth parasites.

TL;DR: Together, adaptation and loss of genetic capacity are the major contributors to overall reproductive fitness and accidental selection is genetically associated with adaptation, but is not goal‐directed.
Journal ArticleDOI

Intermediary metabolism in the dauer larva of the nematode Caenorhabditis elegans— 1. Glycolysis, gluconeogenesis, oxidative phosphorylation and the tricarboxylic acid cycle

TL;DR: The dauer larva possesed a considerable capacity to metabolise glycogen, as evident from the high phosphofructokinase activity relative to adult, and these metabolic changes form part of the adaptive response which enables dauer larvae to survive for several months without feeding.
References
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Journal Article

Protein Measurement with the Folin Phenol Reagent

TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Thin layer chromatography

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Thin Layer Chromatography

TL;DR: The idea of using a chromatographic adsorbent in the form of a thin layer fixed on an inert rigid support seems to have been suggested by Izmailov and Shraiber in 1938.
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