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The Impact of SARS-CoV-2 Infection on Youth Mental Health: A Narrative Review

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TLDR
It seems important to pay attention to the mental health of young people in relation to the consequences of the COVID-19 pandemic, however, studies with more robust methodologies and longer follow-ups are needed to establish precise indications for targeted interventions in this context.
Abstract
Background: COVID-19 pandemic has affected the physical health, psychological wellbeing, and mental health of the whole population. Young people are among those most at risk of developing mental health symptoms or disorders related to the pandemic. Purpose: the present narrative review is aimed at providing an updated overview of the current literature concerning the psychological impact of the SARS-CoV-2 infection but also of the COVID-19 outbreak, environmental restriction, and social distancing on mental health outcomes among the youth population aged between 15 and 25 years. Methods: in December 2021, an electronic search on this topic was performed on PubMed. Relevant publications from January 2020 until December 2021 were included. Findings: 53 cross-sectional studies, 26 longitudinal studies, 4 ecological studies, 1 qualitative study, and 1 systematic review were included. We found many methodological limitations in the studies included, especially poor choice of study samples and short follow-ups. Little literature was in support of a strong relationship between SARS-CoV-2 infection and consequences on youth mental health. On the contrary, many studies showed how extraordinary measures to limit the spread of the virus have impacted young people in terms of onset of new mental disorders and symptoms, suicidality, and access to emergency psychiatric services. Depressive and anxiety symptoms and disorders show the greatest increase in incidence, especially in girls and young women. Conclusions: it seems important to pay attention to the mental health of young people in relation to the consequences of the COVID-19 pandemic. However, studies with more robust methodologies and longer follow-ups are needed to establish precise indications for targeted interventions in this context.

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References
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Journal ArticleDOI

The psychological impact of quarantine and how to reduce it: rapid review of the evidence.

TL;DR: A review of the psychological impact of quarantine using three electronic databases is presented in this article, where the authors report negative psychological effects including post-traumatic stress symptoms, confusion, and anger.
Journal ArticleDOI

The psychological impact of the COVID-19 epidemic on college students in China.

TL;DR: Having relatives or acquaintances infected with COVID-19 was a risk factor for increasing the anxiety of college students and economic effects, and effects on daily life, as well as delays in academic activities, were positively associated with anxiety symptoms.
Journal ArticleDOI

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

TL;DR: Preliminary data from patients with inflammatory disorders, as well as medically healthy depressed patients, suggest that inhibiting proinflammatory cytokines or their signaling pathways may improve depressed mood and increase treatment response to conventional antidepressant medication.
Journal ArticleDOI

Impact of COVID-19 pandemic on mental health in the general population: A systematic review.

TL;DR: The COVID-19 pandemic is associated with highly significant levels of psychological distress that, in many cases, would meet the threshold for clinical relevance.
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