Journal ArticleDOI
The recurrence of whooping cough: possible implications for assessment of vaccine efficacy
Paul E. M. Fine,J. A. Clarkson +1 more
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Though overall pertussis incidence fell in England and Wales subsequent to the introduction of vaccination on a national scale in the 1950s, pertussi epidemics have continued to occur regularly every 3-4 years, surprising that the interepidemic period did not decrease after the 1974 fall in vaccine uptake.About:
This article is published in The Lancet.The article was published on 1982-03-20. It has received 148 citations till now. The article focuses on the topics: Vaccine efficacy & Whooping cough.read more
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Journal ArticleDOI
Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies
Seema Mattoo,Jonathan D. Cherry +1 more
TL;DR: DTaP vaccines, which are less reactogenic than DTP vaccines, are now in general use in many developed countries, and it is expected that the expansion of their use to adolescents and adults will have a significant impact on reducing pertussis and perhaps decrease the circulation of B. pertussedis.
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Herd Immunity: History, Theory, Practice
TL;DR: This new popularity of herd immunity comes as a consequence of several recent major achievements of vaccination programs, i.e.: the historic success of the global smallpox eradication program; dramatic increases in vaccination coverage stimulated by national programs and by the Expanded Programme on Immunization.
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Seasonality and period-doubling bifurcations in an epidemic model
Joan L. Aron,Ira B. Schwartz +1 more
TL;DR: It is shown that small amplitude periodic solutions exhibit a sequence of period-doubling bifurcations as the amplitude of seasonal variation increases, predicting a transition to chaos of the kind studied in other biological contexts.
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Epidemiology of pertussis.
TL;DR: Despite high coverage rates for primary immunization in infants and children, pertussis continues to be a global concern, with increased incidence widely noted, and a general shift in the age distribution of pertussedis toward older groups is highlighted.
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Opposite Patterns of Synchrony in Sympatric Disease Metapopulations
TL;DR: Analysis of measles epidemics in UK cities shows the reverse pattern, namely a shift from spatial incoherence and irregularity before vaccination to regular, synchronous epidemics afterward, and models show that these patterns can arise from disease-specific responses to dynamical noise.