Journal ArticleDOI
The Roles of Unrecognized Mpox Cases, Contact Isolation and Vaccination in Determining Epidemic Size in Belgium: A Modeling Study
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In this article , the authors used a network model to simulate a mpox epidemic among men who have sex with men and found that vaccination of individuals at highest risk of infection reduces epidemic size more than post-exposure vaccination of sexual partners.Abstract:
Abstract We used a network model to simulate a mpox epidemic among men who have sex with men. Our findings suggest that unrecognized infections have an important impact on the epidemic, and that vaccination of individuals at highest risk of infection reduces epidemic size more than post-exposure vaccination of sexual partners. read more
Citations
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Journal ArticleDOI
Modeling the Impact of Sexual Networks in the Transmission of Monkeypox virus Among Gay, Bisexual, and Other Men Who Have Sex with Men — United States, 2022
Ian H. Spicknall,Emily D. Pollock,Pat Clay,Alexandra M. Oster,Kelly Charniga,Nina Masters,Yoshinori J. Nakazawa,Gabriel Rainisch,Adi V. Gundlapalli,Thomas L. Gift +9 more
TL;DR: Reductions in one-time partnerships, a change in behavior already being reported by MSM, might significantly reduce MPXV transmission.
Journal ArticleDOI
Monkeypox outbreak 2022: What we know so far and its potential drug targets and management strategies
Ali A. Rabaan,Abdul Hawil Abas,Trina Ekawati Tallei,Mona A Al-Zaher,Noor M Al-Sheef,Fatimawali,Esraa Z Al-Nass,Eba A Al-Ebrahim,Yunus Effendi,Rinaldi Idroes,Mather F Alhabib,Hussain A Al-Fheid,Ahmad Akroman Adam,Talha Bin Emran +13 more
TL;DR: In this paper , the authors discuss monkeypox disease, potential drug targets, and management strategies to overcome the monkeypox virus infection, which can result in flu-like symptoms, fever, and a persistent rash.
Posted ContentDOI
Accumulation of immunity in heavy-tailed sexual contact networks shapes monkeypox outbreak sizes
Hiroaki Murayama,Carl A. B. Pearson,Sam Abbott,Fuminari Miura,Sung-mok Jung,Elizabeth Fearon,Sebastian Funk,Akira Endo +7 more
TL;DR: In this paper , a mathematical model incorporating empirical estimates of the heavy-tailed sexual partnership distribution among men who have sex with men (MSM) suggests that monkeypox epidemics can hit the infection-derived herd immunity threshold and begin to decline with less than 1% of sexually active MSM population infected regardless of interventions or behavioural changes.
Journal ArticleDOI
Uptake of Mpox vaccination among transgender people and gay, bisexual and other men who have sex with men among sexually-transmitted infection clinic clients in Vancouver, British Columbia
Mark Gilbert,Aidan Ablona,Hsiu Ju Chang,Troy Grennan,Michael A. Irvine,C. Sarai Racey,Travis Salway,Monika Naus,Meena Dawar,Gina Ogilvie +9 more
TL;DR: In this article , the impact of Mpox vaccination campaigns for transgender people and gay, bisexual and other men who have sex with men (T/GBM) was evaluated among clients of an urban STI clinic in British Columbia (BC).
Journal ArticleDOI
The possible effect of socio-behavioral factors and public health actions on the mpox epidemic slowdown
Francesco Vairo,S. Leone,V Mazzotta,Pierluca Piselli,Gabriella De Carli,Simone Lanini,F. Maggi,Emanuele Nicastri,Roberta Gagliardini,S. De Vita,Andrea Siddu,Giovanni Rezza,Alessandra Barca,Francesco Vaia,Andrea Antinori,Enrico Girardi +15 more
TL;DR: In this paper , the authors explore the possible factors affecting the trend of mpox cases in an Italian region (Lazio) with a rapid roll-out of the vaccination campaign.
References
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Journal ArticleDOI
Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022
TL;DR: The monkeypox virus infection in humans was seldom reported outside African regions where it is endemic as mentioned in this paper , and currently cases are occurring worldwide, but transmission, risk factors, clinical presentation, and outcomes of infection are poorly defined.
Journal ArticleDOI
Community transmission of monkeypox in the United Kingdom, April to May 2022
TL;DR: The first sustained sustained MPXV transmission in the UK was reported between 7 and 25 May, with human-to-human transmission through close contacts, including in sexual networks as discussed by the authors .
Journal ArticleDOI
Retrospective detection of asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium
Irith De Baetselier,Christophe Van Dijck,Chris Kenyon,J. Coppens,Johan Michiels,Tessa De Block,Hilde Smet,Sandra Coppens,Fien Vanroye,Joachim Jakob Bugert,Philipp Girl,Sabine Zange,Laurens Liesenborghs,Isabel Brosius,Johan van Griensven,Philippe Selhorst,Eric Florence,Dorien Van den Bossche,Kevin K. Ariën,Antonio Mauro Rezende,Koen Vercauteren,Marjan Van Esbroeck,Kadrie Ramadan,Tom Platteau,K. Van Looveren,Jolien Baeyens,Cindy Van Hoyweghen,M. Mangelschots,Leo Heyndrickx,Anne Hauner,B. Willems,Emmanuel Bottieau,Patrick Soentjens,Nicole Berens,Saskia van Henten,Stefanie Bracke,Thibaut Vanbaelen,Leendert Vandenhove,Jacob Verschueren,Marie Laga,Jef Vanhamel,Bea Vuylsteke +41 more
TL;DR: In this paper , the authors investigated whether undiagnosed infections occurred among men attending a Belgian sexual health clinic in May 2022, and they found that certain cases of monkeypox remain unddiagnosed and suggest that testing and quarantining of individuals reporting symptoms may not suffice to contain the outbreak.
Journal ArticleDOI
Modelling human-to-human transmission of monkeypox.
TL;DR: This work uses mathematical modelling to argue that, in a population with diminishing herd immunity against orthopoxvirus species, the epidemic potential of monkeypox will continue increasing, and monkeypox could emerge as the most important orthop oxvirus infection in humans.
Journal ArticleDOI
Stochastic model for interhuman spread of monreypox
TL;DR: In this article, a computerized stochastic model of Monte Carlo type was constructed to assess the potential risk of the monkeypox virus to establish and maintain itself in an unvaccinated population through continuous man-to-man transmission.
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