Journal ArticleDOI
Therapeutic intervention scoring system
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The Therapeutic Intervention Scoring System (TISS) introduced in 1974 has become a widely accepted method of classifying critically ill patients and in response to requests to update the system, some items have been deleted, some have been added, and certa are added.Abstract:
The Therapeutic Intervention Scoring System (TISS) introduced in 1974 has become a widely accepted method of classifying critically ill patients. In response to requests to update the system because of recent innovations in critical care, some items have been deleted, some have been added, and certaread more
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A controlled trial to improve care for seriously ill hospitalized patients: The study to understand prognoses and preferences for outcomes and risks of treatments (SUPPORT)
Alfred F. Connors,Neal V. Dawson,N. A. Desbiens,William J. Fulkerson,Lee Goldman,William A. Knaus,Joanne Lynn,R. K. Oye,M. Bergner,Ann M. Damiano,R. Hakim,D. J. Murphy,J. Teno,B. Virnig,Douglas P. Wagner,A. W. Wu,Y. Yasui,D. K. Robinson,B. Kreling +18 more
TL;DR: A 2-year prospective observational study (phase I) with 4301 patients followed by a two-year controlled clinical trial (phase II) with 4804 patients and their physicians randomized by specialty group to the intervention group or control group (n=2652).
Journal ArticleDOI
The costs of adverse drug events in hospitalized patients
David W. Bates,Nathan Spell,David J. Cullen,Elisabeth Burdick,Nan M. Laird,Laura A. Petersen,Stephen D. Small,Bobbie Jean Sweitzer,Lucian L. Leape +8 more
TL;DR: The substantial costs of ADEs to hospitals justify investment in efforts to prevent these events, and estimates of annual costs attributable to all ADEs and preventable ADEs for a 700-bed teaching hospital are $5.6 million and $2.8 million are conservative because they do not include the costs of injuries to patients or malpractice costs.
Journal ArticleDOI
Patient Risk Factors for Adverse Drug Events in Hospitalized Patients
David W. Bates,Elizabeth B. Miller,David J. Cullen,Lisa Burdick,Lawrence W. Williams,Nan M. Laird,Laura A. Petersen,Stephen D. Small,Bobbie Jean Sweitzer,Martha Vander Vliet,Lucian L. Leape +10 more
TL;DR: The results suggest that, rather than targeting ADE-prone individuals, prevention strategies should focus on improving medication systems.
Journal ArticleDOI
Clinical symptoms and length of survival in patients with terminal cancer.
TL;DR: The prevalence of similar symptoms among patients with cancer of various primary and metastatic sites also supports the concept of a common final clinical pathway in patients with advanced malignant neoplasms.
Journal ArticleDOI
Influence of combined intravenous and topical antibiotic prophylaxis on the incidence of infections, organ dysfunctions, and mortality in critically ill surgical patients: a prospective, stratified, randomized, double-blind, placebo-controlled clinical trial.
Wolfgang A. Krueger,Franz-Peter Lenhart,Gertraud Neeser,Gotthart Ruckdeschel,Heidi Schreckhase,Hans-Joachim Eissner,Helmuth Forst,Joachim Eckart,Klaus Peter,Klaus Unertl +9 more
TL;DR: Surveillance cultures from tracheobronchial, oropharyngeal, and gastric secretions and from rectal swabs did not show any evidence for the selection of resistant microorganisms in the patients receiving prophylaxis.