Patent
Three-dimensional microfluidics incorporating passive fluid control structures
TLDR
In this article, a three-dimensional microfluidic device (100) formed from a plurality of substantially planar layers (101, 102, 103) sealed together is disclosed.Abstract:
A three-dimensional microfluidic device (100) formed from a plurality of substantially planar layers (101, 102, 103) sealed together is disclosed.read more
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Systems and methods for multi-analysis
TL;DR: In this article, a system for sample processing is described, which is capable of performing one or more of a sample preparation, sample assay, and detection step using a small volume of sample.
Patent
Apparatus and methods for parallel processing of micro-volume liquid reactions
TL;DR: In this paper, the authors present an array of microholes in a substrate to perform multiple simultaneous micro-volume chemical and biochemical reactions in an array format, which can be used for storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting.
Patent
Microfluidic synthesis devices and methods
Stephen D. O'Connor,Christoph D. Karp,Marci Pezzuto,Paren P. Patel,Steven E. Hobbs,Eugene Dantsker +5 more
TL;DR: In this article, a microfluidic reactor for performing chemical and biological synthesis reactions, including chemical syntheses of organic, polymer, inorganic, oligonucleotide, peptide, protein, bacteria, and enzymatic products is provided.
Patent
Assay apparatus and method using microfluidic arrays
John R. Linton,Karl Yoder,Robert A. Hess,Leila Hasan,Robert Ellis,Tanya S. Kanigan,Kristine Friesen,Arrin Katz,Colin J. H. Brenan,Thomas Morrison,Javier Garcia +10 more
TL;DR: In this paper, a system for holding at least one sample and reagent for analysis is described, which includes a pair of parallel covers (22, 23), at least 1 of which is light transmissive, of which pair one forms a top and the other forms a bottom, and a frame between the covers to define, in relation to the covers, an interior volume.
Patent
Integrated health data capture and analysis system
TL;DR: In this article, an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions is presented. But the system can be used to monitor infectious and chronic diseases.
References
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Patent
Integrated nucleic acid diagnostic device
TL;DR: In this paper, a miniaturized integrated nucleic acid diagnostic device and system is presented, which can perform one or more sample acquisition and preparation operations, in combination with one or multiple sample analysis operations.
Patent
Mesoscale polynucleotide amplification device and method
Peter Wilding,Larry J. Kricka +1 more
TL;DR: In this article, the mesoscale flow system includes a polynucleotide polymerization reaction chamber in fluid communication with the inlet port which is provided with reagents required for polymerization and amplification of a preselected polynotide.
Patent
Parallel reaction cassette and associated devices
TL;DR: In this paper, the authors describe a cassette (100) for conducting reactions therein comprising one or more fluid exchange channels (141), a supply chamber (150), a reaction chamber (160), and a waste chamber (170).
Patent
Multi-layer microfluidic devices
TL;DR: In this paper, a multi-layer microfluidic system was proposed by providing additional substrate layers, e.g., third, fourth, fifth and more substrate layers mated with the typically described first and second layers.
Patent
Liquid distribution system
Peter John Zanzucchi,Satyam Choudary Cherukuri,Sterling Eduard Mcbride,Robert R. Demers,Aaron W. Levine +4 more
TL;DR: In this article, the authors proposed a liquid distribution system, which is useful in a number of contexts, including in accomplishing various synthetic, diagnostic and drug screening reactions, using an alpha reservoir and a beta reservoir.