Journal ArticleDOI
Thyroid Hormone and Attention in School‐Age Children with Congenital Hypothyroidism
Joanne Rovet,Miguel Alvarez +1 more
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TLDR
Children with high levels of both hormones were found to be significantly more distractable on an index of cognitive attention but were reportedly less hyperactive.Abstract:
The relationship between attention and thyroid hormone was examined using a retrospective database of 85 7-year-old children with congenital hypothyroidism who received psychological evaluations and thyroid function tests on the same day. Four unique subgroups with different levels of thyroxine and thyrotropin were compared on psychological tasks and measures of attention. Children with high levels of both hormones were found to be significantly more distractable on an index of cognitive attention but were reportedly less hyperactive. Level of thyroxine accounted for over 10% of the variance in attention.read more
Citations
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Journal ArticleDOI
European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism.
Juliane Léger,Antonella Olivieri,Malcolm Donaldson,Toni Torresani,Heiko Krude,Guy Van Vliet,Michel Polak,Gary Butler +7 more
TL;DR: In this paper, a systematic literature search was conducted to identify key articles relating to the screening, diagnosis, and management of congenital hypothyroidism (CH) and the evidence-based guidelines were developed with the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system, describing both the strength of recommendations and the quality of evidence.
Journal ArticleDOI
Neurocognitive Aspects of Hypothyroidism
TL;DR: The commonly held view that hypothyroid dementia is an imminently reversible condition is only partially supported by the medical literature, which is fraught with methodological and conceptual shortcomings.
Journal ArticleDOI
Thyroid disease in pregnancy.
Brian M. Casey,Kenneth J. Leveno +1 more
TL;DR: Thyroid testing during pregnancy should be performed on symptomatic women or those with a personal history of thyroid disease to establish the diagnosis of overt hypothyroidism and the goal of treatment with levothyroxine is to return TSH to the normal range.
Journal ArticleDOI
Congenital hypothyroidism: influence of disease severity and L-thyroxine treatment on intellectual, motor, and school-associated outcomes in young adults.
TL;DR: Long-term outcome revealed enduring cognitive and motor deficits in young adults with CH relative to control subjects andVerbal functions and Arithmetic were associated with L-thyroxine treatment variables, suggesting that more optimal treatment might be possible.
Journal ArticleDOI
Long-term sequelae of hearing impairment in congenital hypothyroidism
TL;DR: Hearing loss and its functional consequences were evaluated retrospectively in children with congenital hypothyroidism and revealed that early speech was delayed in hearing impaired children, whereas deficits persisted in later receptive language and auditory discrimination skills.
References
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Journal ArticleDOI
Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone
Peter Hauser,Alan J. Zametkin,Pedro E. Martinez,Benedetto Vitiello,J A Matochik,A J Mixson,Bruce D. Weintraub +6 more
TL;DR: In the study sample, attention deficit-hyperactivity disorder is strongly associated with generalized resistance to thyroid hormone.
Journal ArticleDOI
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