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Showing papers in "The Journal of Pediatrics in 1996"


Journal ArticleDOI
TL;DR: There is an increasing incidence of non-insulin- dependent diabetes mellitus among adolescents in Greater Cincinnati, accompanying the national rise in adolescent obesity.

1,191 citations


Journal ArticleDOI
TL;DR: Early-onset sepsis remains an important but uncommon problem among VLBW preterm infants and improved diagnostic strategies are needed to enable the clinician to distinguish between the infected and the uninfected V LBW neonate with symptoms and to target continued antibiotic therapy to those who are truly infected.

840 citations


Journal ArticleDOI
TL;DR: Recurrent abdominal pain and symptoms of IBS are commonly noted in a community-based adolescent population and frequently result in use of health care resources, and anxiety and depression scores were significantly higher for students with IBS-type symptoms compared with those without symptoms.

521 citations


Journal ArticleDOI
TL;DR: In this paper, the prevalence and nature of feeding difficulties and oral motor dysfunction among a representative sample of 49 children with cerebral palsy (12 to 72 months of age) were determined using a population survey by means of a combination of interview and home observational measures.

385 citations


Journal ArticleDOI
TL;DR: To determine the minimum volume of blood and the absolute number of organisms required for detection of bacteremia and fungemia by an automated colorimetric blood culture system (BacT/Alert, Organon Teknika).

382 citations


Journal ArticleDOI
TL;DR: Hemangiomas can proliferate in utero and manifest as fully developed tumors at birth and can regress rapidly, raising new questions about the pathogenesis of this tumor.

309 citations


Journal ArticleDOI
TL;DR: Lower mental test scores persisted in infants with iron-deficiency anemia despite extended oral iron therapy and an excellent hematologic response, according to a double-blind, controlled trial in Costa Rica.

286 citations


Journal ArticleDOI
TL;DR: Infection adversely influences PDA outcome by increasing the risk of late ductal reopening and PDA closure failures, and increased levels of prostaglandins and tumor necrosis factor alpha in infants with infection may explain the poor PDA outcomes.

285 citations


Journal ArticleDOI
TL;DR: A placebo-controlled trial among 2067 Indonesian neonates who received either 52 μmol (50,000 IU) orally administered vitamin A or placebo on the first day of life was conducted in this paper.

253 citations


Journal ArticleDOI
TL;DR: Serum procalcitonin was determined in newborn infants at the time of admission to the pediatrics or obstetrics unit and increased levels were found in all neonates with bacterial sepsis, suggesting that procalCitonin might be of value in diagnosing neonatal septicaemia.

245 citations


Journal ArticleDOI
TL;DR: These results provide the basis for a randomized, controlled trial comparing LMWH with standard heparin in pediatric patients and were reduced by 30% because of decreased laboratory monitoring, blood sampling times, intravenous starts, and nursing time.

Journal ArticleDOI
TL;DR: It is suggested that Depo-Provera may, at least temporarily, suppress the expected skeletal bone mineralization in adolescents, whereas Norplant and oral contraceptives are associated with the expected increase in bone density in this population.

Journal ArticleDOI
TL;DR: The data emphasize the importance of other influences, and in particular that of varying systemic vascular resistance, in the determination of blood pressure in preterm infants.

Journal ArticleDOI
TL;DR: Results indicate indirectly that T-helper lymphocytes may play a role in the pathogenesis of MAS, and the use of this drug may circumvent the need for increased doses of corticosteroids in some patients.

Journal ArticleDOI
TL;DR: Systemic AG may involve varying numbers and combinations of extracutaneous sites, and Optimal treatment for symptomatic, unresectable disease is currently undefined but should be selected to minimize toxic effects in children who are typically younger than 1 year old at presentation.

Journal ArticleDOI
TL;DR: Infants and toddlers with obstructive lung disease can be reliably and safely treated with inhaled medication administered with an MDI via a spacer with mask, and the doses given are higher than the currently recommended doses.

Journal ArticleDOI
TL;DR: This classroom-based, public health approach improved children's cardiovascular disease risk profiles; it is practical and fairly easy to incorporate into the school day.

Journal ArticleDOI
TL;DR: Almost one fourth of the CP in VLBW children occurred in infants delivered in level I facilities soon after their mothers' admissions, and almost one fourth was in children who had neonatal seizures after birth to women with chorionitis.

Journal ArticleDOI
TL;DR: Preservative-free topical ointment therapy decreased TEWL for 6 hours after application, decreased the severity of dermatitis, and decreased bacterial colonization of axillary skin, and these data support the use of topical oints in very premature infants during the first weeks after birth.

Journal ArticleDOI
TL;DR: After control for antimicrobial use, white children were still at an increased risk of infection with NSSP, possibly through greater exposure to resistant strains, and increased use of antimicrobial drugs enhances the risk of carriage of NSSP.

Journal ArticleDOI
TL;DR: Four children with Kawasaki disease resistant to treatment with intravenously administered immune globulin who were treated with high doses of methylprednisolone apparently responded with normalization of symptoms, and none had significant progression of coronary artery abnormalities or adverse events.

Journal ArticleDOI
TL;DR: Differences exist among tertiary pediatric hospitals in the nature of the patients admitted with RSV LRI, and randomized clinical trials are needed to determine the efficacy of different drug treatments used to treat infants hospitalized with RSv.

Journal ArticleDOI
TL;DR: The occurrence of PPB appears to herald a constitutional and heritable predisposition to dysplastic or neoplastic disease in approximately 25% of cases and patients with PPB and their families should be investigated carefully.

Journal ArticleDOI
TL;DR: Data refute the hypothesis that continuing regular, vigorous, sustained exercise throughout pregnancy adversely affects morphometric and neurodevelopmental outcome in offspring at 5 years of age and suggest that exercise during pregnancy reduces the subcutaneous fat mass of the offspring.

Journal ArticleDOI
TL;DR: A plasma IL-6 level of 100 pg/ml or greater, obtained before the twelfth hour of life, appears to be an ideal marker for detecting early-onset neonatal infection with a high degree of sensitivity and specificity.

Journal ArticleDOI
TL;DR: Infantile hemangioma and arteriovenous malformation of the liver have a similar presentation but a different natural history, and therefore require different treatment, and combined embolization and surgical resection is recommended for hepatic AVM and for solitary symptomatic hemangsioma, if drug therapy fails.

Journal ArticleDOI
TL;DR: Observations indicate that TGF-Beta 1 may contribute to the fibrotic response that is observed in the lungs of infants who have CLD.

Journal ArticleDOI
TL;DR: It is demonstrated that prenatal exposure to cocaine at sufficiently high doses early in pregnancy has the potential to produce cognitive changes in infants and that more focused, narrow-band tests may be necessary to detect these subtle neurobehavioral effects.

Journal ArticleDOI
TL;DR: It is indicated that significant differences in insulin secretion and sensitivity are detectable in healthy black versus white adolescents.

Journal ArticleDOI
TL;DR: Overall administration of neonatal transfusions has decreased markedly, most likely because of multiple factors, and therapeutic strategies should focus on this group of VLBW infants during this critical period.