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Journal ArticleDOI

Treatment of premenstrual syndrome by spironolactone

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TLDR
The administration of spironolactone reduced weight and relieved psychological symptoms in more than 80 per cent of the symptomatic group and there was no significant difference between symptomatic and asymptomatic groups.
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This article is published in British Journal of Obstetrics and Gynaecology.The article was published on 1979-02-01. It has received 140 citations till now. The article focuses on the topics: Spironolactone.

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Citations
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Journal ArticleDOI

Sex differences in depression and anxiety disorders: potential biological determinants.

TL;DR: Processes which may contribute to increased rates of affective disorders in women are greater fluxes in reproductive hormones across the life span, and increased sensitivity to catecholamine augmentation of emotional memory consolidation.
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Premenstrual syndromes: Overview from a methodologic perspective

TL;DR: The authors offer recommendations to both investigators and clinicians for more careful observation and documentation of the relationship between mood disorders and the menstrual cycle.
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A review of treatment of premenstrual syndrome & premenstrual dysphoric disorder

TL;DR: Preliminary evidence suggests that the drospirenone-containing pill called Yasmin may be effective the treatment of PMDD, and there is good clinical evidence for GnRH analogs with addback hormonal therapy, danocrine, and estradiol implants or patches with progestin to protect the endometrium.
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Oral contraceptives containing drospirenone for premenstrual syndrome.

TL;DR: Two placebo-controlled trials of women with PMDD showed less severe premenstrual symptoms after three months with drospirenone 3 mg plus ethinyl estradiol 20 μg than with placebo, and the groups were also similar for adverse events related to treatment.
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Premenstrual Dysphoric Disorder: Burden of Illness and Treatment Update

TL;DR: In this article, a prospective symptom charting over two menstrual cycles to confirm the timing of the symptoms and to rule out other diagnoses was used to diagnose premenstrual dysphoric disorder (PMDD).
References
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Journal ArticleDOI

The hormonal causes of premenstrual tension

TL;DR: My attention has been increasingly directed to a large group of women who are handicapped by premenstrual disturbances of manifold nature, in whom grave systemic disorders manifest themselves predominantly during the premen menstruation.
Journal Article

Alteration by oral contraceptives of normal menstrual changes in plasma renin activity concentration and substrate.

TL;DR: Two out of 6 hypertensive women taking oral contraceptives in this study were felt to be the cause for the condition and an hypothesis was advanced that suppressed renin secretion was a normal response to elevated substrate levels and that inadequate suppression might account for the hypertensive effect of oral contraceptives.
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Correlations between mood, weight, and electrolytes during the menstrual cycle: a renin-angiotensin-aldosterone hypothesis of premenstrual tension.

TL;DR: The potassium/sodium ratio and weight changes suggest that activation of the renin‐angiotensin‐aldosterone system may underlie increases in psychopathology linked to the menstrual cycle, possibly through effects on central neurotransmitters.