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Journal ArticleDOI

Tricyclazole induces melanin shunt products and inhibits altersolanol a accumulation by Alternaria solani

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TLDR
In this article, the effect of tricyclazole, a known inhibitor of pentaketide-derived melanin biosynthesis, on three Alternaria solani isolates was studied.
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This article is published in Pesticide Biochemistry and Physiology.The article was published on 1988-05-01. It has received 13 citations till now. The article focuses on the topics: Potato dextrose agar & Alternaria solani.

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Fungal melanins: a review

TL;DR: The relationship of polyketide melanogenesis molecular biology to that of nonmelanin-producing pathways in a wide range of fungi and other organisms is discussed and fungal melanin properties are compared with those of animal and bacterial melanins.
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The dark side of the mycelium : Melanins of phytopathogenic fungi

TL;DR: This work focuses on one phytopathogenic fungus, Gaeumannomyces graminis var.
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Enhancing the stress tolerance and virulence of an entomopathogen by metabolic engineering of dihydroxynaphthalene melanin biosynthesis genes.

TL;DR: The transformant, especially under stresses, showed notably enhanced antistress capacity and virulence, in terms of germination and survival rate, infectivity, and reduced median time to death (LT50) in killing diamondback moth larvae compared with the wild type.
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Chlobenthiazone and tricyclazole inhibition of aflatoxin biosynthesis by Aspergillus flavus

TL;DR: The authors showed that chlobenthiazone causes inhibition at a site in the aflatoxin pathway prior to the synthesis of norsolorinic acid, and tricyclazole inhibited the accumulation of aflatoxins B 1, B 2, and B 2a.
References
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Journal ArticleDOI

Biosynthesis and Functions of Fungal Melanins

TL;DR: Three additional discoveries have increased interest among plant pathologists in fungal melanins, including a new class of fungicides that prevent direct penetra­ tion of plant tissue by inhibiting melanin biosynthesis in appressorial cells.
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Melanin biosynthesis in Pyricularia oryzae: site of tricyclazole inhibition and pathogenicity of melanin-deficient mutants.

TL;DR: The data suggest a relationship between melanin biosynthesis and pathogenicity in P. oryzae and five melanin-deficient mutants of P.oryzae that phenotypically resemble the tricyclazole-treated wild-type strain were nonpathogenic or rarely infected two rice varieties.
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Comparisons of fungal melanin biosynthesis in ascomycetous, imperfect and basidiomycetous fungi

TL;DR: Many ascomycetous and related imperfect fungi appear to make melanin from 1,8-dihydroxynaphthalene, whereas basidiomycetes and at least some imperfect fungi probably use alternative pathways.
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Action of the antipenetrant, tricyclazole, on appressoria of Pyricularia oryzae

TL;DR: The antipenetrant, tricyclazole, blocked melanin biosynthesis and protected unwounded, but not wounded, rice plants from infection by a wild-type isolate of Pyricularia oryzae.
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Pentaketide metabolites of verticillium dahliae : Identification of (+)-scytalone as a natural precursor to melanin

TL;DR: Scytalone [3,4-dihydro-3,6,8-trihydroxy-1(2H)naphthalenone] as discussed by the authors was identified as the active metabolite of the brown brm-1 mutant of Verticillium dahliae Kleb.
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