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Journal ArticleDOI

Trimethylorthoformate: A mild and effective dehydrating reagent for solution and solid phase imine formation

Gary C. Look, +3 more
- 24 Apr 1995 - 
- Vol. 36, Iss: 17, pp 2937-2940
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TLDR
Trimethylorthoformate has been found to be an effective dehydrating solvent for the formation of imines, both in the solid phase as well as solution phase.
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This article is published in Tetrahedron Letters.The article was published on 1995-04-24. It has received 141 citations till now. The article focuses on the topics: Imine & Reagent.

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Citations
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Journal ArticleDOI

Schiff bases: A short review of their antimicrobial activities

TL;DR: Schiff bases are aldehyde- or ketone-like compounds in which the carbonyl group is replaced by an imine or azomethine group as discussed by the authors.
Journal ArticleDOI

Solid-phase organic reactions: A review of the recent literature

TL;DR: In this article, the main chemical reactions reported between 1992-October 1995 using solid phase support, focusing upon those suitable for synthesizing small molecules, are presented in graphical format in a table according to reaction types.
Journal ArticleDOI

Schiff Bases: A Short Survey on an Evergreen Chemistry Tool

TL;DR: The review reports a short biography of the Italian naturalized chemist Hugo Schiff and an outline on the synthesis and use of his most popular discovery: the imines, very well known and popular as Schiff Bases.
References
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Book

The chemistry of the carbon-nitrogen double bond

Saul Patai
TL;DR: Patai's Chemistry of Functional Groups as mentioned in this paper is one of chemistry's landmark book series in organic chemistry and is the most complete reference available in functional group chemistry, covering all aspects of the chemistry of an important functional group in each volume, with the emphasis not only on the functional group but on the whole molecule.
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Fluoronaphthyridines as antibacterial agents. 4. Synthesis and structure-activity relationships of 5-substituted-6-fluoro-7-(cycloalkylamino)-1,4-dihydro-4-oxo-1,8- naphthyridine-3-carboxylic acids.

TL;DR: A (3S)-3-amino-pyrrolidine was shown to enhance greatly the in vitro and in vivo activity of the 5-methyl derivative, and was selected as a promising candidate for an improved therapeutic agent.
Journal ArticleDOI

4-Formyl-2-cyclohexenone Derivatives

TL;DR: In this article, the α' carbon was shown to be the site of acylation of a β-alkoxy α,β-unsaturated ketone, i.e. 1 → 2 on formylation.
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