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Journal ArticleDOI

Use of Integra in complex pediatric wounds.

Bahair Ghazi, +1 more
- 01 May 2011 - 
- Vol. 66, Iss: 5, pp 493-496
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TLDR
The usefulness of Integra is well described in the adult reconstructive and burn literature as mentioned in this paper, however, there is limited documentation of its utility in the pediatric plastic surgery population, and only 8 cases referred to us for flap coverage were treated using Integra.
Abstract
The usefulness of Integra is well described in the adult reconstructive and burn literature. There is limited documentation of its utility in the pediatric plastic surgery population. We presented 8 cases referred to us for flap coverage that were treated using Integra. These cases describe difficult wounds resulting from trauma, and congenital abnormalities. The charts of all 8 cases were retrospectively reviewed. There were 5 females and 3 newborns. The average age at coverage with Integra was 4.6 years (range, 1 day―16 years). There were 4 traumatic wounds, 2 cases of cutis aplasia, I myelomeningocele, and 1 case of congenitally absent cranium. The average time to coverage was 8 days, and all trauma patients underwent at least 2 prior washout procedures. The average area covered was 43 cm 2 (range, 6―100 cm 2 ). At a mean follow-up of 14.25 months (range, 9―20 months), 7 patients' wounds had healed without need for further flap coverage. Only 1 patient required a skin graft over the Integra bed. There was 1 infection resulting in total dermal matrix loss and need for local flap reconstruction. One patient developed severe hypertrophic scarring requiring surgical revision. Integra is a reliable option in pediatric reconstruction, which may save a child the morbidity of a more extensive procedure.

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Citations
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Journal ArticleDOI

The use of Integra® Dermal Regeneration Template in the reconstruction of traumatic degloving injuries.

TL;DR: Evaluation of the success of a dermal regeneration template followed by a split-thickness autograft in the treatment of complex traumatic degloving injuries at an American College of Surgeons verified Level 1 Trauma Center found it a viable alternative to traditional methods of repair.
Journal ArticleDOI

Evidence-Based Medicine: Lower Extremity Acute Trauma

TL;DR: Preference by both physicians and patients tend to favor the course to limb salvage, but it must be appreciated by the caregiver that it is always the patient who has to live with the residua of an altered limb and lifestyle.
Journal ArticleDOI

Aplasia cutis congenita: clinical management and a new classification system.

TL;DR: The authors emphasize the role of emergency split-thickness skin grafting in the treatment of large aplasia cutis congenita or ones with large veins or sagittal sinus exposure and offer a treatment guideline.
Journal ArticleDOI

Pediatric Thermal Burns and Treatment: A Review of Progress and Future Prospects.

TL;DR: A new promising approach has been presented as a first-line therapy in the treatment of burns to reduce surgical autografting in pediatric patients and a review article focuses on thermal burn pathophysiology and pain management.
Journal ArticleDOI

Infectious Complications Associated with the Use of Integra: A Systematic Review of the Literature.

TL;DR: While Integra offers many benefits, surgeons must be aware that infectious complications are not uncommon, and a careful risk–benefit analysis of its use in reconstruction must be performed, and open discussion with the patient preoperatively regarding infection rate is of utmost importance.
References
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Journal ArticleDOI

An objective long-term evaluation of Integra (a dermal skin substitute) and split thickness skin grafts, in acute burns and reconstructive surgery

TL;DR: This research aimed to provide objective data on the long-term outcome of Integra and objectively demonstrated that the elastic properties of areas treated with Integra is comparable to normal skin.
Journal ArticleDOI

Integra Artificial Skin® for burn scar revision in adolescents and children

TL;DR: Comparison of pre- and postoperative findings revealed a significant functional improvement in all and a considerable cosmetic improvement inAll but two patients, suggesting that Integra is a valid new treatment modality for extensive burn scar revision in younger patients.
Journal ArticleDOI

Seven years' experience with Integra as a reconstructive tool.

TL;DR: The bilayered dermal substitute Integra (Integra Life Sciences Corp., Plainsboro, NJ) was developed and has been widely used as primary coverage for excised acute burns.
Journal ArticleDOI

Reconstruction of full thickness scalp defects after tumour excision in elderly patients: our experience with Integra dermal regeneration template.

TL;DR: In the scalp defect reconstructions after tumor excision, Integra allows to obtain a thicker and more durable coverage than skin graft on the skull, allowing to detect a tumor recurrence earlier than a flap reconstruction with no risk of burying an eventual underlying residual tumor.
Journal ArticleDOI

Experience of Integra® in cancer reconstructive surgery

TL;DR: In complex cases the use of Integra® is found to be a safe and viable alternative to traditional methods of wound closure in cases where excision was required down to bone or tendon.
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