Journal ArticleDOI
Xanthogranuloma of bone: a challenging imitator of malignancy.
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TLDR
The case of a 44-year-old male who was evaluated at The Johns Hopkins Hospital for a 2.3-cm painful soft tissue mass present within the medullary canal of the distal tibia with destruction of the overlying cortex is reported.Abstract:
Xanthogranulomatous disease of bone is exceptionally uncommon. Clinically, radiologically and pathologically, it is a great imitator of malignancy. While there are few reports on the surgical pathology of this rare entity, there is no published report on its cytopathologic characteristics. We report herein the case of a 44-year-old male who was evaluated at The Johns Hopkins Hospital for a 2.3-cm painful soft tissue mass present within the medullary canal of the distal tibia with destruction of the overlying cortex. A computed tomography-guided fine needle aspiration biopsy revealed abundant histiocytes and occasional giant cells in an inflammatory background. This was interpreted as a 'histiocyte-rich lesion,' and an excisional biopsy was recommended. Subsequent curettage was performed, and the histological material was diagnosed as 'xanthogranuloma of bone.' The rarity of xanthogranuloma of bone and its resemblance to the more common reactive and malignant bone neoplasms may present diagnostic challenges.read more
Citations
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Journal ArticleDOI
Multifocal bilateral xanthogranulomatous osteomyelitis.
TL;DR: The authors present a case of multifocal xanthogranulomatous osteomyelitis involving the left medial malleoli, left talus and the right cuboid bones.
Journal ArticleDOI
Xanthogranulomatous Osteomyelitis of the Tibia.
TL;DR: The patient was not treated with the routine therapy used in previously reported cases (curettage), suggesting that antibiotic therapy should be considered before employing surgical interventions for XO.
Journal ArticleDOI
Xanthogranulomatous osteomyelitis of the distal tibia: a case report
Yoichi Kaneuchi,Takahiro Tajino,Michiyuki Hakozaki,Hitoshi Yamada,Kazuhiro Tasaki,Osamu Hasegawa,Kazuo Watanabe,Shinichi Konno +7 more
TL;DR: A previously healthy 36-year-old Japanese woman presented with a 2-week history of right ankle pain which caused ankle pain in an otherwise healthy woman, and was diagnosed with XO, an extremely rare inflammatory disease which occurs predominantly in males with no characteristic age distribution.
Journal ArticleDOI
A Rare Case Report on Xanthogranulomatous Osteomyelitis of Hip Mimicking Tuberculosis and Review of Literature.
TL;DR: It is important for the surgeons to keep XO in the list of differentials in cases with lytic lesions of bone and assessment should include microbiological culture along with the biopsy.
Journal ArticleDOI
Multiple subcutaneous xanthogranuloma at juxta-articular sites with bone cystic changes resembling rheumatoid arthritis: A case report
TL;DR: An adult patient with multiple subcutaneous xanthogranuloma at juxta-articular sites with bone cystic changes, manifesting similar clinical profiles to rheumatoid arthritis is reported.
References
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Journal ArticleDOI
Risk factors for osteomyelitis
TL;DR: An approach that is useful in classifying the risk factors for the development of acute osteomyelitis is the same as one commonly employed to discuss the mechanisms responsible for pathogenesis: hematogenous dissemination, direct inoculation, and contiguous spread from an adjacent area of soft tissue infection.
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Xanthogranulomatous funiculitis and orchiepididymitis: report of 2 cases with immunohistochemical study and literature review.
TL;DR: Two patients with xanthogranulomatous inflammation are described, one with involvement of the spermatic cord and the other with 1 testicle and epididymis affected, and differential diagnoses with other lesions that are rich in macrophages, such as malakoplakia, and those testicular neoplasms without serologic tumor markers are discussed.
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Cytologic diagnosis of osseous lesions: a review with emphasis on the diagnosis of primary neoplasms of bone.
TL;DR: Current utilization of FNA continues to de‐emphasize its application to the diagnosis of primary lesions of the musculoskeletal system.
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Cytomorphology of Langerhans cell histiocytosis
Pohar-Marinsek Z,Us-Krasovec M +1 more
TL;DR: The cytomorphologic pattern of LCHs in fine needle aspiration biopsy smears is usually characteristic, and a correct diagnosis is possible, especially with the aid of immunocytochemistry, however, one must be aware of different morphologic patterns of L CHs and of unusual appearances of LCs, which may lead to diagnostic errors.
Journal ArticleDOI
Xanthogranulomatous inflammation presenting as a submucosal mass of the sigmoid colon.
Young Ha Oh,Sang Seokg Seong,Kiseok Jang,Yong Woo Chung,Chang Hee Paik,Yong Wook Park,Dong Soo Han +6 more
TL;DR: Although XGI may rarely occur in the large bowel, it should be considered in patients with a colonic submucosal mass, and it is important to make an intraoperative pathological diagnosis in order to avoid any excessive operative stress.