Journal ArticleDOI
Yellow nail syndrome: a case report and review of treatment options
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TLDR
The case of a 67‐year‐old man with YNS and a detailed review of current treatment options are presented and strengthened the literature on this topic.Abstract:
Background and Aims
Yellow nail syndrome is a rare disorder involving characteristic nail changes, lymphedema and chronic respiratory symptoms. Currently there is no definitive treatment and there have been no prospective randomised controlled trials evaluating the available options. In order to strengthen the literature on this topic, we present the case of a 67-year-old man with YNS and a detailed review of current treatment options.
Methods
We included 40 articles for the final review according to their relevance with the subject.
Results
Data for use of the commonly chosen therapies for YNS remains inconclusive, with small studies and case reports showing mixed results of efficacy.
Conclusion
Although the date indicates that it is reasonable to recommend a trial of conservative therapy including vitamin E, antibiotics and compression stockings before pursuing more aggressive or invasive modalities, larger scale studies are required to determine the true efficacy of all treatment options.read more
Citations
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Journal ArticleDOI
Global impact of bronchiectasis and cystic fibrosis.
TL;DR: The disease is highly diverse in its presentation, requiring all respiratory physicians to have knowledge of the different “bronchiectasis syndromes”, with nontuberculous mycobacterial disease predominating in some parts of North America, post-infectious and idiopathic disease predomsinating in Western Europe, and post-tuberculosis bronchiECTasis dominating in South Asia and Eastern Europe.
Journal ArticleDOI
Yellow Nail Syndrome Presenting With a Pericardial Effusion: A Case Report and Review of the Literature.
Laura C. Soong,Richard M. Haber +1 more
TL;DR: The case of a middle-aged man presenting with dystrophic, thickened yellow nails; an idiopathic pericardial effusion in the absence of pleural effusion(s); and unilateral apical bronchiectasis found on computed tomography of the chest is reported.
Journal ArticleDOI
Nail changes, lymphedema, and respiratory symptoms.
TL;DR: A 59-year-old man presented to the authors' clinic with a 2.5-year history of progressive painful yellow discoloration and deformation of the fingernails and toenails, accompanied by lower extremity lymphedema, with complete resolution of nail signs and symptoms at 2 years.
Journal ArticleDOI
Yellow nail syndrome.
TL;DR: The case of a patient with yellow nail syndrome who had yellow, thickened nails unresponsive to antifungal treatment with concomitant lower-extremity lymphedema and a negative pulmonary workup despite chronic cough is presented.
Journal ArticleDOI
Congenital yellow nail syndrome presenting with eyelid lymphedema and fetal hydrops.
Jihane El Alami,Lionel Galicier,Sandra Huynh,Laure Frumholtz,Martine Bagot,Adèle de Masson,Stéphane Vignes,Jean-David Bouaziz +7 more
TL;DR: A child having congenital YNS with several features, including congenital nail dystrophy, pleural effusion, and eyelid and lower-limb lymphedema is described.
References
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Journal ArticleDOI
The "yellow nail" syndrome.
P.D. Samman,William F. White +1 more
TL;DR: The title is used to describe a nail dystrophy which although not rare has received very little mention in earlier literature, and the main features are slow growing disrolourod nails and oedema.
Journal ArticleDOI
Yellow nails, lymphoedema, and pleural effusions.
TL;DR: The thesis is that an otherwise unexplained pleural effusion may occur in patients with chronic lymphoedema and be due to some deficiency in the lymphatics draining the pleural space.
Journal ArticleDOI
Pulmonary Manifestations of the Yellow Nail Syndrome
TL;DR: The association of primary lymphedema with yellow discoloration of the nails has been termed the “yellow nail syndrome,” and a third manifestation may be otherwise unexplained pleural effusion.
Journal ArticleDOI
Yellow nail syndrome.
TL;DR: It is hypothesize that primary stromal sclerosis may lead to lymphatic obstruction, thus explaining the clinical manifestations of yellow nail syndrome and the histopathologic findings of the nail matrix and bed are reported.
Journal ArticleDOI
Yellow nail syndrome: analysis of 41 consecutive patients.
TL;DR: In most cases, YNS is an acquired disorder and associated respiratory manifestations are generally manageable with a regimen of medical and surgical treatments and yellow nails improve in about one half of patients, often without specific therapy.