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Zinc in the Animal Organism: A Review

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TLDR
This paper focuses on zinc metabolism and homeostasis, with an emphasis placed on the biological function of zinc, and deals with zinc deficiency and its effect on health.
Abstract
Abstract Zinc, as an essential metal, is necessary for the correct function of an organism. It is involved in biochemical processes that affect the immune response of an organism, and it acts as a neuromodulator in the excitatory synapses of the brain. Zinc is also applied in response to stressful stimuli. Zinc is an essential factor of gene expression and is important, at the cellular level, in maintaining the integrity of the cell walls. It influences organism ageing. Zinc is relatively abundant in nature, and it exists in a mineral form and rarely as a pure element. Zinc is used widely in industry and agriculture. In industry, it is utilized mainly in the processing of other metals as protection against corrosion. In agriculture, it is used in fertilizers and chemicals to produce pesticides. In certain areas affected by human activities, its concentrations increase, and large quantities of this metal can get into the food supply. In this paper, we focus on zinc metabolism and homeostasis, with an emphasis placed on the biological function of zinc. This study also deals with zinc deficiency and its effect on health. We also touch on the excessive intake of zinc and its toxicity.

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Towards Zero Zinc Oxide: Feeding Strategies to Manage Post-Weaning Diarrhea in Piglets.

TL;DR: In this paper, a comprehensive framework for ZnO utilization and its broad mode of action is presented, and all the risks related to pharmacological ZNO levels are presented; moreover, European institutions’ decisions subsequently.
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Iron requirements of broiler breeder hens.

TL;DR: The study was composed of 3 phases: adaptation to cages, depletion (deficient diet containing 18.7 ± 0.47 ppm Zn) for 7 wk, and experimental phases, which found the non‐linear statistical models were the ones that best fit the results in this study.
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Effect of different levels of organic zinc supplementation on pork quality

TL;DR: In this paper , the effect of two supplementation levels of zinc glycinate (ZnGly) on performance, carcass characteristics, and meat quality of growing-finishing pigs was investigated.
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Effects of Zinc Glycinate on Growth Performance, Serum Biochemical Indexes, and Intestinal Morphology of Yellow Feather Broilers.

TL;DR: In this article, the effects of zinc glycinate (Gly-Zn) on growth performance, serum biochemical index, intestinal morphology, and hepatic metallothionein (MT) mRNA expression in the liver of yellow feather broilers were investigated.
References
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Journal ArticleDOI

The neurobiology of zinc in health and disease

TL;DR: The use of zinc in medicinal skin cream was mentioned in Egyptian papyri from 2000 BC, and the number of biological functions, health implications and pharmacological targets that are emerging for zinc indicate that it might turn out to be 'the calcium of the twenty-first century'.
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The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

TL;DR: Observations support the view that the cysteine-switch mechanism is applicable to all members of this gene family and offers the opportunity for multiple modes of physiological activation of these important enzymes.
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Trace elements in agroecosystems and impacts on the environment

TL;DR: Soil microorganisms are the first living organisms subjected to the impacts of metal contamination, and changes in microbial biomass, activity, and community structure as a result of increased metal concentration in soil may be used as indicators of soil contamination or soil environmental quality.
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Metallothionein: the multipurpose protein

TL;DR: Understanding of the multi-faceted role of MT is enhanced by use of mice with altered gene expression, emphasised in this review.
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Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

TL;DR: It is reported that both human and chicken MMP-2, free of tissue inhibitors of metalloproteinases (TIMPs) are capable of cleaving soluble, triple helical type I collagen generating the ¾- and ¼-length collagen fragments characteristic of vertebrate interstitial collagenases.
Trending Questions (1)
How does Zinc impact the biological processes within living organisms?

Zinc impacts immune response, acts as a neuromodulator, influences gene expression, maintains cell integrity, and affects organism aging. It is essential for biological processes within living organisms.