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Supplements such as CoQ10 and alpha-tocopherol significantly improve sperm count.
The results suggest that seminal fluid improves sperm survival, even if the sperm are from a different male.
Apparently, it affects sperm quality more adversely than it does sperm production.
These effects alter sperm parameters.
but probably also affects the sperm oxidase.

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Can manipulating the seminal microbiome improve fertility outcomes in men?
5 answers
Manipulating the seminal microbiome shows promise in improving fertility outcomes in men. Studies have revealed that alterations in the seminal microbiota composition are associated with changes in semen quality and fertility status. Specific microbial taxa like Lactobacillus have been linked to improvements in semen parameters, while Prevotella has shown a negative impact on sperm quality. Furthermore, certain bacteria like Ureaplasma urealyticum, Enterococcus faecalis, and Mycoplasma hominis have been associated with decreased semen parameters, while Lactobacillus appears to protect sperm quality. These findings suggest that manipulating the seminal microbiome, potentially through probiotics, could be a novel therapeutic approach to enhance male fertility. However, further research with larger studies is needed to fully understand and validate the impact of such interventions on fertility outcomes.
What is the title of the article written by M.A. Rahman in Chem. Sci. J. in 2011?
5 answers
The article written by M.A. Rahman in Chem. Sci. J. in 2011 is titled "Biorthogonal Functions Related to Basic Hypergeometric Integrals with Coupled Continuous and Discrete Components". This article delves into the study of biorthogonal functions associated with basic hypergeometric integrals that encompass both continuous and discrete elements. The research explores the significance of these integrals in various fields such as superconformal indices for three-dimensional quantum field theories and solvable lattice models. Rahman's work in this article presents explicit biorthogonal systems derived from products of Rahman's biorthogonal rational $${}_{10}W_9$$-functions or their degenerate forms. Additionally, the article introduces new bilateral extensions of the Jackson and q-Saalschutz summation formulas, along with novel continuous and discrete biorthogonality measures for Rahman's functions.
What is artificial contraception?
4 answers
Artificial contraception refers to methods or devices used to prevent pregnancy. Various inventions have been developed in this field, such as artificial contraceptive hymens containing spermicides for contraception. Additionally, artificial insemination condoms have been designed with sperm delivery channels to improve the success rate of artificial insemination. Studies have shown that while many women use artificial contraceptives, some are dissatisfied due to risks like cervical cancer, blood clots, and loss of sexual function, leading them to seek safer options. These artificial contraceptive methods aim to provide secure, sanitary, and effective means of birth control, contributing to the prevention of unwanted pregnancies and promoting reproductive health in society.
Stability issues of edible nanoparticles in Food matrices?
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Stability of edible nanoparticles in food matrices is a critical concern due to their impact on the efficacy and safety of nano-encapsulated bioactive compounds. Factors affecting stability include the type and quantity of biopolymers, pH, heating, ionic strength, storage conditions, and gastrointestinal digestion. Techniques like ultracentrifugation and polyethylene glycol extraction, as well as size exclusion chromatography, play crucial roles in stabilizing edible plant-derived nanoparticles. The instability of nanoparticle size in dispersed systems hinders their effective use and increases production costs, emphasizing the need for stabilizing agents like dispersed matrices. Research gaps exist in understanding the fate, interactions with the gastrointestinal tract, and long-term effects of nanoparticles in food, necessitating further systematic studies for comprehensive safety assessments.
What is the difference between conventional and cryoprotectant free sperm cryopreservation?
5 answers
Conventional sperm cryopreservation involves freezing sperm with the use of cryoprotectants, while cryoprotectant-free sperm cryopreservation, known as vitrification, does not require these additives. Studies show that cryoprotectant-free vitrification leads to better recovery rates of motility and sperm quality compared to conventional freezing methods. Cryoprotectant-free vitrification has been found to induce fewer biological changes in sperm, with higher post-thaw recovery rates of motility and vitality, as well as reduced DNA fragmentation. Additionally, vitrification has shown to better preserve sperm features, such as acrosome integrity and cytoskeleton structure, making it a promising alternative for sperm preservation in assisted reproductive technologies.
Why is better to use cryoprotectant free sperm cryopreservation?
5 answers
Cryoprotectant-free sperm cryopreservation is advantageous due to its ability to induce minor biological changes in spermatozoa compared to conventional freezing methods, as shown in. This method, involving direct plunging into clean liquid air, has been found to be a safe alternative to liquid nitrogen vitrification, preserving sperm physiological parameters effectively. Additionally, the use of honey as a natural cryoprotectant in fertility preservation has shown promising results, with improved post-thaw quality and viability, making it a non-toxic and efficient option for cryopreservation. Furthermore, rapid-freezing methods with self-prepared cryoprotectants have demonstrated comparable results to slow freezing, making them a convenient and effective choice for small-volume sperm cryopreservation, especially in cases of severe oligozoospermia.
What are the drawbacks of using cryoprotectants for sperm cryopreservation?
5 answers
The drawbacks of using cryoprotectants for sperm cryopreservation include potential cell damage, reduced motility, and negative effects on embryo quality. Cryoprotectants can lead to cell injury, affecting embryo quality. Additionally, high concentrations of non-penetrative cryoprotectants may cause excessive cell shrinkage and solute effects, potentially damaging cells. In donkey semen cryopreservation, the absence of permeable cryoprotectants resulted in reduced motility, vitality, and membrane integrity of sperm. Furthermore, common contraindications related to cryopreservation in bovine spermatozoa include the presence of ice crystals, oxidative stress, and possible toxicity of cryoprotectants, all impacting sperm quality and fertility potential. These findings highlight the importance of optimizing cryoprotectant formulations to minimize adverse effects during sperm cryopreservation.
For what species royal jelly used for sperm cryopreservation?
5 answers
Royal jelly (RJ) has been studied for its potential benefits in sperm cryopreservation across various species. Research has focused on its effects on sperm characteristics, viability, and motility. Studies have investigated the impact of RJ supplementation on rooster spermatozoa in both liquid and frozen storage conditions. Additionally, RJ has been explored in cattle bulls to enhance post-frozen-thawed sperm characteristics, antioxidant status, and sperm resistance. Furthermore, the use of RJ in Tris-egg yolk and Tris-soybean extenders has been evaluated for its effect on the sperm quality of Damascus buck chilled semen. Moreover, RJ has shown promising results in improving motility, viability, and acrosome integrity of bovine spermatozoa during post-thaw incubation, indicating its potential as a semen extender to enhance sperm quality and fertility.
Why royal jelly uses for sperm cryopreservation?
5 answers
Royal jelly (RJ) is utilized for sperm cryopreservation due to its beneficial effects on sperm characteristics and antioxidant status. Studies on cattle bulls, roosters, and boars have shown that RJ supplementation improves post-frozen-thawed sperm characteristics, viability, and antioxidant capacity, leading to enhanced sperm resistance and conception rates. RJ supplementation at specific concentrations (5 mg/ml in roosters and 1% in boars) has been particularly effective in maintaining sperm motility, viability, and membrane integrity during liquid and frozen storage. Additionally, RJ has been reported to have antioxidant, anti-inflammatory, and immunomodulatory functions, contributing to its positive impact on sperm quality and fertility. Overall, the use of RJ in sperm cryopreservation is supported by its ability to enhance sperm quality and protect against oxidative stress.
What are the specific genetic mutations associated with abnormalities caused by sperm DNA?
5 answers
Specific genetic mutations associated with abnormalities caused by sperm DNA include mutations in genes such as DNAH1, DNAH6, DNAH8, and DNAH10. DNAH1 mutations, such as c.8170.C>T and c.4670C>T, have been linked to severe defects in sperm flagella, impairing sperm motility and leading to male infertility. Similarly, a frameshift mutation in DNAH6 (c.2823dupT) has been identified in individuals with asthenoteratozoospermia, affecting sperm morphology and ultrastructure. Compound heterozygous mutations in DNAH8 have also been associated with multiple morphological abnormalities of sperm flagella (MMAF), leading to severe asthenoteratospermia and male infertility. Furthermore, bi-allelic variants in DNAH10 have been found to cause MMAF in affected men, resulting in flagellar defects and male infertility. These genetic mutations play crucial roles in sperm flagellar assembly and function, impacting male fertility.
How does the use of feed supplements affect sperm quality in low doses?
5 answers
The use of feed supplements has a significant impact on sperm quality in low doses. Anandamide supplementation in extenders enhances post-thaw quality of low sperm doses during cryopreservation in bulls, increasing motile and live spermatozoa proportions while reducing moribund spermatozoa. Nutritional supplementation in boars leads to improved seminal parameters like volume, concentration, agglutination, and motility, resulting in increased profitability with enhanced sperm quality. Additionally, the addition of Minoxvit feed additive positively influences buck sperm quality by increasing volume, motility, viability, and concentration of sperm, indicating an improvement in semen quality. Conversely, exposure to low doses of TCDD negatively affects mouse sperm quality, leading to abnormalities in sperm head, increased apoptosis, and cytotoxicity, highlighting the detrimental impact of environmental pollutants on reproductive health.