How are experiments with virus with aerosol performed?
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Experiments with aerosolized viruses are performed using various methods. One approach involves using simulation models to mimic virus infection and measure the concentration of virus droplet aerosols inside and outside masks in real time, providing information on mask protection rates and respiratory protection . Another method involves developing aerosol filter media made of granular material, such as whey protein nanofibrils and iron oxyhydroxides nanoparticles, which have high filtration efficiencies for both enveloped and non-enveloped viruses . In animal models, aerosol inhalation methods have been established for infecting animals with influenza viruses, including nonhuman primates, allowing for broader infection throughout the lungs . Additionally, a bioaerosol experiment system has been developed to measure virus stability, where virus-laden droplets are generated, evaporated, and suspended for a designed period to evaluate virus exposure risks in indoor environments . Another technique involves the detection of aerosolized viruses using field-effect-transistor-based methods, where virus-antibody-bound particles are delivered to the transistor during detection, indicating the presence of a virus .
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| Papers (5) | Insight |
|---|---|
14 Citations | The paper describes a technique for the detection of aerosolized viruses using electro-aerodynamic deposition. The virus and antibody solutions are mixed, aerosolized, and then charged using a corona discharge. |
| The paper describes the development of a bioaerosol experimental system for virus stability measurement. The system involves generating virus-laden droplets using a Collison nebulizer, evaporating the droplets in a mixing chamber, and then suspending the droplet nuclei in a Goldberg Drum for sampling and stability measurement. The experiments involve controlling temperature, humidity, and particle size throughout the process. | |
8 Citations | The paper describes the experimental infection of cynomolgus macaques with a highly pathogenic H5N1 influenza virus through the aerosol route using a nebulizer. |
| The experiments with virus aerosols were performed using a compact experimental setup with a filtration holder, compressed air tanks, and a nebulizer unit. Virus-containing solutions were nebulized and carried through the filtration media, and the trapped aerosols were analyzed for infectivity and genome count. | |
| Experiments with virus aerosol are performed using a virus droplet aerosol infection interactive simulation experiment system, which includes simulation models of infected and healthy individuals, masks, respirators, and particle counters. |
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