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How do the physical connection of endosomes to other compartments within the cell appears essential? 


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The physical connection of endosomes to other compartments within the cell appears essential for cellular integration and coordination of various functions. Endosomes communicate with organelles such as the endoplasmic reticulum (ER), mitochondria, the plasma membrane (PM), and the nuclear envelope, allowing for the exchange of materials and information between cellular compartments . The endosomal system, with its complex membranous network, operates as a coherent unit to optimize cellular responses and maintain homeostasis . The endoplasmic reticulum (ER) has emerged as a key organizer of endosome biology, contributing to endosomal transport and positioning . Endosomes also play a role in modulating and compartmentalizing cell signaling, connecting the plasma membrane with intracellular events . Overall, the physical connection of endosomes to other compartments enables the integration of cellular processes, regulation of signaling pathways, and maintenance of cellular homeostasis .

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The physical connection of endosomes to other compartments within the cell appears essential for their positioning and transport.
The physical connection of endosomes to other compartments within the cell is essential for maintaining intracellular dynamics and coordinating cellular functions.
Journal ArticleDOI
Maria C. Zanellati, Sarah R. Cohen 
16 Dec 2022-Science
The physical connection of endosomes to other compartments within the cell is essential for the exchange of materials and information between organelles.

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