How does medical chemistry contribute to the treatment of specific disease ?
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Medicinal chemistry plays a crucial role in the treatment of specific diseases by contributing to the discovery and development of new therapeutic agents . It focuses on designing molecules with high potency, low toxicity, and selectivity to overcome drug resistance and target specific cells . Additionally, modifications like covalently coupling blocking groups to drugs can prevent metabolic conversion and enhance drug selectivity . Stem cell research benefits from medicinal chemistry through the identification of small molecules that control stem cell fate, aiding in tissue repair and regeneration . The discipline involves designing, synthesizing, and evaluating novel compounds against therapeutic targets, considering their physicochemical properties and pharmacokinetics for effective drug discovery programs .
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| Papers (5) | Insight |
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6 Citations | Medicinal chemistry aids in designing, synthesizing, and evaluating novel compounds targeting specific diseases, enhancing drug discovery programs by optimizing therapeutic potential and pharmacokinetic properties. |
315 Citations | Medical chemistry contributes by identifying small molecules that selectively control stem cell fate, aiding in tissue repair and regeneration for diseases like cardiovascular disease, neurodegenerative disease, and cancer. |
1 Citations | Medicinal chemistry contributes by developing novel molecules with high potency, low toxicity, and selectivity to target diseases like cancer, cardiovascular diseases, and HIV, overcoming drug resistance and improving treatment efficacy. |
| Medical chemistry contributes by modifying drugs with blocking groups to enhance specificity. This reduces cytotoxicity, lowers dosages, and increases selectivity by preventing metabolic conversion in non-target cells. | |
3 Citations | Medicinal chemistry aids in discovering new medications for treating depression comorbid with inflammatory diseases by predicting structure-activity relationships and exploring existing drug activities. |
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