How does Polyethylene glycol protect bacteria?
Best insight from top research papers
Polyethylene glycol (PEG) protects bacteria through various mechanisms. PEG grafting alters surface properties, inhibiting initial bacterial adhesion and biofilm formation . When immobilized on surfaces, PEG reduces bacterial adhesion and biofilm formation, making it an effective antibacterial agent . Additionally, PEG-based coatings can incorporate quorum sensing inhibitors, hindering bacterial communication and biofilm formation while reducing cell attachment . Furthermore, chemically bonding long-chain PEG on dental biomaterials reduces bacterial adhesion, addressing oral health issues related to biofilm formation . Overall, PEG's antifouling properties, inhibition of bacterial adhesion, and potential to disrupt bacterial communication contribute to its effectiveness in protecting against bacterial colonization and biofilm formation.
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| Papers (5) | Insight |
|---|---|
61 Citations | Polyethylene glycol forms a stable water layer through hydrogen bonding, preventing bacterial adhesion and biofilm formation on dental materials, thus protecting against bacterial accumulation. |
| Polyethylene glycol-based coatings inhibit bacterial colonization by combining low biofouling properties with a quorum-sensing inhibitor, hindering bacterial communication and reducing cell attachment and adhesion. | |
| Polyethylene glycol (PEG) is covalently tethered to Nylon 6 surfaces via N,N'-disuccinimidyl carbonate, reducing bacterial adhesion, making it a potential material for fighting pathogenic bacteria. | |
40 Citations | Polyethylene glycol (PEG) resists bacterial adhesion by forming a hydrated barrier that repels bacteria, inhibiting their attachment to surfaces, as shown in the study. |
06 Mar 2023 | Polyethylene glycol (PEG) prevents bacterial adherence by reducing protein adsorption on hydrophobic surfaces, achieved through dense PEG grafting via PEI, leading to minimal bacterial attachment. |
Related Questions
Can crossinker polyethylene glycol increase thermal stability?5 answersYes, crosslinking polyethylene glycol (PEG) can indeed increase thermal stability. Research has shown that the addition of PEG can enhance the stability of materials like shellac and coal by forming more stable linkages. Moreover, in the case of polyethylene vitrimers, dynamic cross-linking with 4,4′-dithiodianiline led to an increase in the onset degradation temperature and decomposition rate, indicating improved thermal stability with increased cross-linking density. Additionally, the grafting of 1-(4-vinyloxy)phenylethenone (VPE) onto polyethylene molecules during cross-linking processes improved the thermal stability of the resulting composite, inhibiting thermal migration and enhancing stability. Therefore, crosslinking PEG or related compounds can be an effective strategy to enhance the thermal stability of various materials.
How does graphene oxide affect the bacteria?5 answersGraphene oxide (GO) affects bacteria through multiple mechanisms. Firstly, GO can attach to the bacterial cell surface either in parallel or perpendicular interaction modes, depending on the surface oxygen content (SOC) of the GO. The interaction mode is related to the rigidity of the GO, with high SOC GO being more flexible and able to wrap bacteria, while lower SOC GO tends to contact bacteria with their edges. Secondly, GO can cause damage to the cellular ultrastructure of bacteria, with Ag-GO causing the most severe damage and GO causing intermediate damage. The damage is correlated with specific Fourier transform infrared spectroscopy (FTIR) spectral metrics, indicating disruption of the lipopolysaccharide, peptidoglycan, and phospholipid bilayers. Additionally, GO can decrease the ability of bacteria to form biofilms on surfaces, reducing biofilm formation on implantable medical devices. Finally, GO exhibits antimicrobial activity by inducing cellular damage, oxidative stress, and limiting physical movements and metabolism of bacteria.
What are the effects of glyceryl polyethyleneglycol ricinoleate on animal health?4 answersGlyceryl polyethyleneglycol ricinoleate (PEG castor oil) has been found to be safe for use as a technological feed additive for various animal species. It has been determined that PEG castor oil is safe at specific concentrations in complete feed for different animal species, including chickens, laying hens, turkeys, piglets, pigs, dairy cows, rabbits, veal calves, cattle, sheep, goats, horses, cats, dogs, salmonids, and ornamental fish. Another study found that glyceryl monolaurate (GML), a different compound, can improve the laying performance, egg quality, immune function, and intestinal barrier function of laying hens. Additionally, GML has been shown to positively affect nutrient utilization and performance in broiler chickens, even in diets with decreased energy levels. However, there is no specific information available on the effects of glyceryl polyethyleneglycol ricinoleate on animal health in the provided abstracts.
What are the chemical properties of polyethylene glycol?5 answersPolyethylene glycol (PEG) has several chemical properties. It can dissolve a wide range of chemicals, including mineral salts. PEG also has acid/base functionalities that allow it to serve as a catalyst. It can complex metal cations and engage in redox chemistry. PEG can be combined with other green solvents and functionalized to enhance its properties. Physicochemical studies of PEG as a solvent are ongoing, indicating the need for further research in this area. Additionally, PEG can form gels under certain conditions, which can affect its rheological properties.
What are the advantages and disadvantages of polyethylene glycol?5 answersPolyethylene glycol (PEG) has several advantages and disadvantages. One advantage is that PEG can act as a plasticizer and coupling agent in rubber compounds, improving their dispersion and preventing chemical reactions with filler particles. PEG is also widely used as a pre-procedural agent in colonoscopy due to its excellent cleansing effect and low loss of electrolytes and moisture. However, PEG can have a salty taste, which may decrease patient compliance. Additionally, PEG is used as a binder material for fibers and for adhering superabsorbent particulate materials, which can be advantageous in certain applications. PEG is a versatile product with a wide range of applications, but its taste and potential for decreased patient compliance should be considered.
How do we make polyethylene glycol blend with water?5 answersPolyethylene glycol (PEG) can be blended with water by using various methods. One method involves synthesizing PEG through a reaction process that includes adding ethylene glycol or diethylene glycol into a reaction kettle, followed by the addition of ethylene oxide and conducting a series of reactions and purification steps. Another method involves preparing a thickening agent for an emulsion in water by dehydrating PEG using an organic solvent and then adding various agents to the reaction system. Additionally, PEG can be used in the preparation of hydrophilic membranes for oil-water separation, where it is introduced into the polymer solution to enhance phase-inversion and produce high permeability membranes. Furthermore, PEG can be used in the formation of alginate gel fibers by mixing with polyols, such as PEG, which disrupts the assembly of extended alginate chains and forms alginate-PEG complexes. Finally, PEG can be coagulated in water by adding an acidic colloidal solution of a specified substance, such as melamine-aldehyde, which causes the PEG to become insoluble and separate from the water.