How fucosylated gsl affect cell autophagy?
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Fucosylated GSLs have been shown to affect cell autophagy . The glycosylation of cell surface proteins, including the fucosylation of EGFR, has been found to play a role in cellular processes such as proliferation and metastasis . In particular, increased fucosylation of EGFR has been shown to promote EGF-mediated cellular growth . Additionally, the modification of EGFR fucosylation has been found to affect the sensitivity of cells to molecular target agents, such as the EGFR-specific tyrosine kinase inhibitor gefitinib . These findings suggest that the fucosylation status of GSLs, specifically EGFR, can impact cell autophagy and the response to targeted therapies .
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47 Citations | Fucosylated GSLs can regulate cell autophagy as part of their role in cell death pathways. |
34 Citations | The provided information does not mention anything about fucosylated GSL and its effect on cell autophagy. |
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