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The results from depletion/repletion studies indicate that serum zinc concentrations respond appreciably to severe dietary zinc restriction, although there is considerable interindividual variation in these responses.
Our findings demonstrate that zinc absorption can be measured in humans from single foods containing a physiological dose of zinc by using the whole-gut lavage absorption technique and that zinc bioavailability from beef is about fourfold greater than from a high-fiber breakfast cereal.
In five of six subjects a drop in urinary zinc to below 150 micrograms/day was noted before a decrease in plasma zinc to less than 70 micrograms/100 g, indicating that urinary zinc responds more rapidly than plasma zinc to dietary changes and may be useful for evaluating zinc nutriture.
Low serum zinc concentrations are reversible with zinc supplementation.
The results demonstrate that sweat zinc is the sample of choice for the assessment of zinc status and that leucocyte zinc is almost as useful.
The population mean serum zinc concentration is a useful indicator of the successful delivery and absorption of zinc supplements in children.
Zinc status of the individual may also influence adjustments in fractional zinc absorption.
Serum zinc is thought to be a reasonable indicator of zinc status.
Plasma zinc concentration is a useful method of evaluating oral zinc absorption from doses of 10 to 50 mg. Urinary zinc excretion is an alternative method of assessing zinc absorption, particularly when doses of 50 to 100 mg of elemental zinc are administered.
The results of the present experiment indicate that the zinc tolerance test, that is, an unequivocal rise in serum zinc following per oral administration of this metal, provides the best indication of zinc status.
The assay is quick, convenient, and in principle measures functionally available zinc.
Zinc absorption in humans could be improved by zinc complexation with gluconate.
The large changes in zinc intake, excretion, and absorption-even when considered together-only explained modest reductions in plasma zinc mass.
Our results found no evidence of zinc deficiency or of changes on the kinetic parameters of zinc in patients with insulin-dependent diabetes mellitus following a venous zinc tolerance test.
In conclusion, the present experiment showed that zinc sulphate and zinc gluconate are equally efficient as zinc supplements in salmon feeds within the concentrations normally found in salmon feed.