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Impact of commensal microorganisms on individual health?

Pathogenic bacteria

Inflammasome complex

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Commensal microorganisms play a crucial role in individual health by influencing various aspects of the host's physiology. These microorganisms interact with the host's immune system, biochemistry, and metabolic processes, impacting health and disease outcomes. The gut microbiota, in particular, produces metabolites like short-chain fatty acids (SCFA) that can influence the pathogenic potential of bacteria isolated from individuals with and without Inflammatory Bowel Disease (IBD). Changes in the microbial composition, especially in disease states like IBD, can lead to altered host responses and inflammation. Understanding these host-microbe interactions and the influence of factors like SCFA on commensal bacteria is essential for developing targeted therapeutic strategies to maintain individual health and prevent disease progression.

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Open access•Journal Article•DOI A50 impact of short chain fatty acids on pathogenicty of commensal bacteria in pediatric inflammatory bowel diseases Michael Bording-Jorgensen, T. Gartke, H Armstrong, Eytan Wine - Show less +3 more 21 Feb 2022-Journal of the Canadian Association of Gastroenterology	The composition of short-chain fatty acids influences the pathogenicity of commensal bacteria in pediatric IBD, potentially impacting host health through altered inflammatory responses and invasion capabilities.
Open access•Journal Article•DOI Interaction between the inflammasome and commensal microorganisms in gastrointestinal health and disease. Daisuke Watanabe, Yijie Guo, Nobuhiko Kamada - Show less +2 more 27 Oct 2021-Embo Molecular Medicine 12 Citations	Commensal microorganisms interact with the inflammasome, influencing gastrointestinal health. This interaction can impact inflammation, cell death, and disease pathogenesis in the host.
Book Chapter•DOI Individual microbiota correction and human health: programming and reprogramming of systemic and local immune response 01 Jan 2022	Commensal microorganisms can regulate human health individually through personalized pharmabiotics and targeted nutrition, impacting conditions like vaginitis, diabetes, caries, and periodontitis, highlighting the importance of microbiome in health.
Book Chapter•DOI Commensal Microbes and Their Metabolites: Influence on Host Pathways in Health and Cancer Roberto Mendez, Sulagna Banerjee, Santanu Banerjee - Show less +2 more 01 Jan 2021 1 Citations	Commensal microbes and their metabolites influence host pathways in health, impacting individual health through interactions with the host's metabolic processes, immune system, and disease pathogenesis.
Journal Article•DOI The Effect of Microbiota on Cardiovascular Health and Disease Mediha Sert, Zeynep B Ozer - Show less +1 more 02 Nov 2022-Kardiyovasküler hemşirelik dergisi	Commensal microorganisms, particularly intestinal microbiota, significantly impact individual health, influencing cardiovascular diseases and metabolic conditions through immune responses, inflammation, and vascular changes.

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