Is AIDS caused by a virus that contains RNA?
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99 Citations | In this situation the raise of HIV RNA could also originate from release of wild‐type viruses, caused by activation of the latent virus reservoir. |
78 Citations | These results support the role of HIV-1 RNA expression in the development of AIDS. |
19 Citations | While it is likely that some of this viral RNA is in noninfectious particles, it derives from virus-infected cells that are making viral protein and RNA. |
17 Citations | The results indicate that visna virus contains RNA. |
Another possibility is that the AIDS virus is a mutation of a known nonpathogenic virus. | |
It appears unlikely, therefore, that RNA is a constituent of either virus. | |
32 Citations | Since no prominent subgenomic virus-specific RNA was identified in infected cells, an RNA species of this size may also act as a messenger RNA. |
The current finding that a widespread and successful RNA virus is recombinant provides support for such an hypothesis. | |
Moreover, we could also demonstrate that viral RNA is present in free virus. | |
To our knowledge, this is the first report showing that endogenous nonretroviral RNA virus elements may function in antiviral defense, providing a potential role for RNA virus endogenization in host evolution. |