Is the flu caused by an RNA virus?
Answers from top 10 papers
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| Papers (10) | Insight |
|---|---|
89 Citations | We propose that mvRNAs act as the main agonists of RIG-I during influenza virus infection. Aberrant mini viral RNAs, which are produced by erroneous RNA polymerase activity during the replication of the viral RNA genome, act as the main agonists of RIG-I during influenza virus infection. |
20 Citations | s/Significance These findings suggested that influenza A virus may acquire an RNA polymerase adapted to different body temperatures of the host by reassortment of the RNA polymerase genes. |
| Influenza virus is thus unique among nononcogenic RNA viruses in synthesizing its mRNA in the nucleus. | |
231 Citations | Influenza virus is a negative strand RNA virus and is one of the rare RNA viruses to replicate in the nucleus. |
63 Citations | It is possible that host cell DNA-dependent RNA polymerase is involved in the replication of influenza virus RNA. |
185 Citations | Here we show that the NS1 protein of human influenza A virus has an RNA silencing suppression activity in plants, similar to established RNA silencing suppressor proteins of plant viruses. |
| We have produced the first potential therapeutic DI virus for the clinic by cloning an influenza A DI RNA (1/244) which was derived naturally from genome segment 1. | |
| The data indicate that the 22 5' terminal and the 26 3' terminal bases of the influenza A virus RNA are sufficient to provide the signals for RNA transcription, RNA replication, packaging of RNA into influenza virus particles. | |
55 Citations | These findings support the hypothesis that the influenza virus genome is divided among several distinct pieces of RNA. |
| It appears unlikely, therefore, that RNA is a constituent of either virus. |