Isolation of Quercetin from plant extract
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Quercetin, a bioactive compound, has been successfully isolated from plant extracts in several studies. Muhammad Zahoor et al. developed a method for large-scale production of quercetin from Rubus fruticosus fruit, achieving high recovery rates through a membrane system and magnetic carbon nanocomposite . Rohit Kumar Bijauliya et al. isolated and classified quercetin from Dalbergia sissoo (L.) using chromatography techniques and spectroscopy . Le Huy Hoang et al. investigated acidic hydrolysis under ultrasound-assisted conditions to release quercetin from plant extracts, obtaining quercetin-containing hydrolyzed extracts from various plants . Sonal Desai and Pratima Tatke discussed various methods for isolation and analytical methods for quercetin-3-O-β-D-Glucoside (QG), a marker compound for plant extracts . Dorota Wianowska et al. highlighted the use of the sea sand disruption method (SSDM) for the estimation of quercetin and its derivatives in plants, eliminating errors in plant metabolism studies .
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| Yes, the study focuses on the isolation of quercetin from the Rubus fruticosus fruit extract. | |
1 Citations | Yes, Quercetin was isolated from the ethanolic fraction of Dalbergia sissoo (L.) leaf extract using column chromatography and spectroscopic techniques. |
Related Questions
What is Quercetin?5 answersQuercetin is a flavonoid with diverse pharmacological activities found in fruits, vegetables, and plants, either naturally or as a supplement. It exhibits antioxidant, anti-inflammatory, antiviral, and anticancer properties. Studies highlight its potential in combating various cancers, including oral, breast, colon, liver, lung, and prostate cancers. Quercetin's mechanisms include inducing apoptosis, inhibiting tumor progression, and modulating the tumor microenvironment. Moreover, it shows promise in antiviral activities against influenza A, Hepatitis C, Dengue, and Ebola viruses by targeting viral proteins and enzymes. In prostate cancer, quercetin demonstrates antitumor effects by increasing apoptosis, arresting the cell cycle, and reducing migration potential, albeit with potential resistance mechanisms involving modulation of cancer-promoting genes. Overall, quercetin's multifaceted benefits make it a valuable compound with potential applications in various health conditions.
What are advantages of quercetin?5 answersQuercetin, a flavonoid found in plants, fruits, and vegetables, offers numerous health benefits. It exhibits antioxidant, anti-inflammatory, and cognitive enhancement properties. Quercetin has been shown to reduce the release of harmful neutrophil extracellular traps (NETs), protecting against tissue damage induced by inflammation. Additionally, quercetin demonstrates anticancer effects, inhibiting cell viability, survival, and proliferation in oral cancer cells, while also reducing metastatic potential and drug resistance. Moreover, quercetin has been found to possess anti-inflammatory, antioxidant, and anti-proliferative activities against prostate malignancy, inducing apoptosis, arresting cell cycle progression, and reducing migration and colony-forming capabilities of cancer cells. Overall, quercetin's diverse pharmacological effects make it a promising natural compound for various health conditions.
What are the benefits of quercetin?5 answersQuercetin, a flavonoid found in fruits and vegetables, has numerous health benefits. It has strong antioxidant properties, which help scavenge free radicals and protect against cellular damage. Quercetin also exhibits anti-inflammatory effects by inhibiting the production of inflammatory cytokines and enzymes. Additionally, it has been shown to have anticancer effects by inhibiting cancer cell proliferation and inducing apoptosis. Quercetin has cardiovascular benefits as well, such as lowering blood pressure and reducing cholesterol levels. It may also have positive impacts on immune function and allergy symptoms. Furthermore, quercetin has been studied for its potential neuroprotective properties and its ability to modulate inflammation and oxidative stress. Overall, quercetin shows promise as a therapeutic agent for various conditions and has potential applications in nutraceuticals, pharmaceuticals, and functional foods for promoting overall well-being and disease prevention.
What are the (micro)organisms that can produce quercetin?5 answersQuercetin can be produced by various microorganisms. Sphingomonas sanxanigenens strains can be fermented to prepare quercetin. Gut microbes such as Escherichia coli, Stretococcus lutetiensis, Lactobacillus acidophilus, Weissella confusa, Enterococcus gilvus, Clostridium perfringens, and Bacteroides fragilis have been found to have the ability to degrade quercetin, with C. perfringens and B. fragilis having the strongest ability. Bacterial cultures like Bacillus cereus can also transform quercetin into other compounds such as protocatechuic acid and quercetin-3-glucoside (isoquercitrin). Additionally, cultured cells of Euphorbia milli have been found to contain quercetin glucuronide in a large amount.
Why is quercetin used as a standard for food products?5 answersQuercetin is used as a standard for food products because of its potential biological effects and its ability to improve the nutritional profiles of food matrices. It is a flavonoid with antioxidant, anti-inflammatory, and anti-allergic properties, making it beneficial for human health. Quercetin can be found in a wide variety of plant resources, such as onions, black tea, broccoli, and grapes. However, the bioavailability of quercetin is often relatively low, which limits its effectiveness. To overcome this, researchers have developed strategies to enhance its oral bioavailability, such as encapsulating it in colloidal delivery systems. Additionally, quercetin has been incorporated into bio-based packaging films for active food packaging, improving the physical and functional properties of the film and extending the shelf life of fresh foods. Overall, quercetin's diverse biological properties and its potential to improve food products make it a valuable standard in the food industry.
Isolation of quercetin from the plants4 answersQuercetin has been isolated from various plants in the studies conducted by Alebiosu et al., Zahoor et al., and Akbar et al.. Alebiosu et al. isolated a quercetin derivative from the plant Centaurea perrottetii using silica gel column and gel filtration chromatography. Zahoor et al. developed a method for large-scale production of quercetin from Rubus fruticosus fruit using optimized silica gel columns and membrane systems. Akbar et al. isolated quercetin from Digera muricata using different chromatographic techniques and identified its herbicidal activity against weeds. Additionally, Astutiningsih conducted a study on okra (Abelmoschus esculentus L.) and isolated quercetin from the plant, which showed inhibitory power on the alpha amylase enzyme. These studies demonstrate the isolation of quercetin from different plants and highlight its potential pharmacological activities.