What is known about viscoelASTICITY OF CHROMATIN?
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The viscoelasticity of chromatin has been investigated in several studies. It has been found that the diffusion behavior of particles in chromatin deviates from the traditional Stokes-Einstein relation, indicating a non-sticky diffusion process . At short times, large particles are temporarily "caged" by chromatin spatial constraints, forming effective domains . The viscoelastic properties of the nuclear interior of a living human cell have been characterized, showing a transition from a viscous fluid to a viscoelastic medium depending on the size of the tracer proteins . The chromatin network in the cell nucleus is suggested to form a random obstacle network rather than a self-similar structure . These findings provide insights into the physical properties of chromatin and how it affects enzymatic reactions and target search processes within the nucleus.
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| Papers (5) | Insight |
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| The paper provides evidence that the nuclear interior, including chromatin, exhibits viscoelastic properties on intermediate scales, which vary with protein size. | |
10 Citations | The paper investigates the viscoelastic response of model interphase chromosomes and calculates the elastic and viscous moduli of chromatin. |
1 Citations | The paper presents a dynamic model that takes into account the effects of viscoelasticity in the framework of the standard model of the linear body. It does not specifically discuss the viscoelasticity of chromatin. |
| The paper investigates the viscoelastic response of model interphase chromosomes by tracking the motion of dispersed Brownian particles. It calculates the elastic and viscous moduli of interphase chromosomes. | |
| The provided paper does not discuss the viscoelasticity of chromatin. |
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