What is the cost for bacteriophage production?
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The cost of bacteriophage production varies depending on the scale and methodology employed. Economic analyses comparing traditional methods like PEG precipitation to newer approaches like Aqueous Two-Phase Systems (ATPS) show that ATPS can become more cost-effective with material cost discounts, ranging from $52.2 to $1.72 per gram at different scales . Modeling studies for scaled-up production of bacteriophages suggest that the best cost-effective process configuration involves using one bioreactor for production, followed by filtration steps, resulting in a production cost of US$ 0.02 per chicken for supplying a portion of the poultry market . Computational models can optimize bacteriophage production, with simulations indicating that production costs and productivity can vary significantly based on operational parameters like substrate concentration and cycling times .
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12 Citations | The cost for bacteriophage production using Aqueous Two-Phase Systems (ATPS) ranges from $52.2 to $1.72 per gram, depending on material costs discount and operation scale. |
4 Citations | The cost for bacteriophage production can be optimized using computational modeling to minimize costs or maximize productivity, as detailed in the paper. |
18 Citations | The production cost per chicken for a six bacteriophages mixture to control Salmonella in poultry is US$ 0.02, as determined by bioprocess modeling and economic analyses. |
26 Citations | Efficient bacteriophage production processes aim for low costs. Various operation modes like batch, semi-continuous, and continuous are explored to optimize productivity and minimize expenses. |
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