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What is the current state of research on the topic of ASL applied to "focal ischemia"? 


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Research on ASL applied to focal ischemia has made significant advancements. Studies have highlighted the utility of ASL in evaluating patients with stroke-like symptoms, showing a negative predictive value of 94% for acute ischemic stroke detection . Additionally, technical developments in ASL methods have enhanced its capabilities, including advancements in image reconstruction, noise reduction, and quantification of nonperfusion parameters . Furthermore, the use of 3D-pCASL has shown promise in early evaluation, differential diagnosis, and prognosis assessment of ischemic cerebrovascular diseases like focal ischemia, indicating a broad application prospect for ASL in this area . Overall, these findings underscore the growing importance and effectiveness of ASL in the context of focal ischemia research.

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Current research provides guidance on ASL in acute ischemic stroke, emphasizing disease-specific parameters for sequence optimization and interpretation, aiding in diagnosis of focal ischemia in clinical neuroimaging.
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The research status of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling (3D-pCASL) in ischemic cerebrovascular diseases shows promise in evaluating focal ischemia, aiding in diagnosis and treatment decisions.
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