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António J. Bastos-Leite
Researcher at University of Porto
Publications - 31
Citations - 1081
António J. Bastos-Leite is an academic researcher from University of Porto. The author has contributed to research in topics: Dementia & Hyperintensity. The author has an hindex of 12, co-authored 30 publications receiving 888 citations. Previous affiliations of António J. Bastos-Leite include VU University Medical Center & VU University Amsterdam.
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Journal ArticleDOI
Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: The CADDementia challenge
Esther E. Bron,Marion Smits,Wiesje M. van der Flier,Hugo Vrenken,Frederik Barkhof,Philip Scheltens,Janne M. Papma,Rebecca M. E. Steketee,Carolina Méndez Orellana,Rozanna Meijboom,Madalena Pinto,Joana R. Meireles,Carolina Garrett,António J. Bastos-Leite,Ahmed Abdulkadir,Olaf Ronneberger,Nicola Amoroso,Roberto Bellotti,David Cárdenas-Peña,Andrés Marino Álvarez-Meza,Chester V. Dolph,Khan M. Iftekharuddin,Simon Fristed Eskildsen,Pierrick Coupé,Vladimir S. Fonov,Katja Franke,Christian Gaser,Christian Ledig,Ricardo Guerrero,Tong Tong,Katherine R. Gray,Elaheh Moradi,Jussi Tohka,Alexandre Routier,Stanley Durrleman,Alessia Sarica,Giuseppe Di Fatta,Francesco Sensi,Andrea Chincarini,Garry Smith,Zhivko Stoyanov,Lauge Sørensen,Mads Nielsen,Sabina Tangaro,Paolo Inglese,Christian Wachinger,Martin Reuter,John C. van Swieten,Wiro J. Niessen,Stefan Klein +49 more
TL;DR: A grand challenge to objectively compare algorithms based on a clinically representative multi-center data set of three diagnostic groups, finding the best performances were achieved using feature extraction based on voxel-based morphometry or a combination of features that included volume, cortical thickness, shape and intensity.
Journal ArticleDOI
The Contribution of Medial Temporal Lobe Atrophy and Vascular Pathology to Cognitive Impairment in Vascular Dementia
António J. Bastos-Leite,Wiesje M. van der Flier,Elisabeth C.W. van Straaten,Salka S. Staekenborg,Philip Scheltens,Frederik Barkhof +5 more
TL;DR: Investigating the relative contribution of cerebrovascular disease and MTA to cognitive impairment in patients fulfilling diagnostic criteria for VaD found that patients with higher grades of MTA or large vessel VaD had significantly worse general cognitive and executive functioning, whereas associations with small vessel disease were restricted to worse executive functioning.
Journal ArticleDOI
Reliability and sensitivity of visual scales versus volumetry for evaluating white matter hyperintensity progression.
Alida A. Gouw,W.M. van der Flier,E.C.W. van Straaten,Leonardo Pantoni,António J. Bastos-Leite,Domenico Inzitari,Timo Erkinjuntti,Lars-Olof Wahlund,Charlotte Ryberg,R. Schmidt,Franz Fazekas,Philip Scheltens,Frederik Barkhof +12 more
TL;DR: To determine change in WMH, dedicated progression scales are more sensitive and/or reliable and correlate better with volumetric volume change than cross-sectional scales.
Journal ArticleDOI
Dysconnectivity Within the Default Mode in First-Episode Schizophrenia: A Stochastic Dynamic Causal Modeling Study With Functional Magnetic Resonance Imaging
António J. Bastos-Leite,Gerard R. Ridgway,C. Silveira,Andreia Norton,Salomé Reis,Karl J. Friston +5 more
TL;DR: Reduced effective connectivity to the AF node of the DMN is revealed—reflecting a reduced postsynaptic efficacy of prefrontal afferents—in patients with first-episode schizophrenia.
Journal ArticleDOI
Variability of physiological brain perfusion in healthy subjects - A systematic review of modifiers. Considerations for multi-center ASL studies.
Patricia Clement,Henk-Jan Mutsaerts,Lena Václavů,Eidrees Ghariq,Francesca B. Pizzini,Marion Smits,Marjan Acou,Jorge Jovicich,Ritva Vanninen,Mervi Könönen,Roland Wiest,Egill Rostrup,António J. Bastos-Leite,Elna-Marie Larsson,Eric Achten +14 more
TL;DR: A theory of ‘deep MRI physiotyping’ is inferred from the combined knowledge of factors influencing brain perfusion as a strategy to reduce variance by taking both personal information and the presence or absence of perfusion modifiers into account.