What is the effect Epicatechin on myostatin?
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Epicatechin has been shown to have an inhibitory effect on myostatin expression . Several studies have demonstrated that epicatechin consumption in humans leads to an improvement in the follistatin to myostatin ratio, indicating an increase in follistatin levels and a decrease in myostatin levels . In a study conducted on patients with Becker muscular dystrophy, epicatechin supplementation resulted in a decrease in myostatin levels . Additionally, epicatechin has been found to inhibit myostatin gene expression in skeletal muscle in response to cycling exercise training . These findings suggest that epicatechin has a positive effect on myostatin regulation, leading to an increase in follistatin levels and a decrease in myostatin levels.
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| Papers (4) | Insight |
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| Epicatechin treatment normalized the blood levels of myostatin, a recognized inducer of muscle atrophy, in the ovariectomy-induced loss of skeletal muscle structure-function in female rats. | |
24 Citations | The effect of Epicatechin on myostatin is not mentioned in the provided paper. |
| The paper states that the consumption of Epicatechin (EPI) in humans is associated with the inhibition of myostatin (MTSN) and the induction of follistatin (FST), resulting in an improvement in the FST:MSTN ratio. | |
| The qualitative analysis in the paper shows that Epicatechin has an inhibitory action on myostatin expression. |
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