G
George F. Schreiner
Researcher at Baylor College of Medicine
Publications - 84
Citations - 7532
George F. Schreiner is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Vascular endothelial growth factor & Kidney. The author has an hindex of 37, co-authored 84 publications receiving 7083 citations. Previous affiliations of George F. Schreiner include Washington University in St. Louis & Ewha Womans University.
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Journal ArticleDOI
The progression of renal disease.
TL;DR: It is anticipated that different diseases associated with glomerular sclerosis will be found to depend to varying extents on these two potential mechanisms of sclerosis: the capacity of both intrinsic cells and infiltrating cells to alter the microenvironment of the glomerulus so that sclerosis progresses inexorably long after the disappearance of the initiating insult.
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Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress POTENTIAL ROLE IN FRUCTOSE-DEPENDENT AND -INDEPENDENT FATTY LIVER
Miguel A. Lanaspa,Laura G. Sánchez-Lozada,Yea Jin Choi,Christina Cicerchi,Mehmet Kanbay,Carlos A. Roncal-Jimenez,Takuji Ishimoto,Nanxing Li,George Marek,Murat Duranay,George F. Schreiner,Bernardo Rodriguez-Iturbe,Takahiko Nakagawa,Duk Hee Kang,Yuri Y. Sautin,Richard J. Johnson +15 more
TL;DR: It is shown that fructose also stimulates triglyceride synthesis via a purine-degrading pathway that is triggered from the rapid phosphorylation of fructose by fructokinase, which provides new insights into the pathogenesis of hepatic fat accumulation under normal and diseased states.
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Role of the Microvascular Endothelium in Progressive Renal Disease
Duk Hee Kang,John Kanellis,Christian Hugo,Luan D. Truong,Sharon Anderson,Dontscho Kerjaschki,George F. Schreiner,Richard J. Johnson +7 more
TL;DR: Evidence that progressive renal disease is characterized by a progressive loss of the microvasculature is presented and there is intriguing evidence that stimulation of angiogenesis and/or capillary repair may stabilize renal function and slow progression.
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CTGF Expression is Induced by TGF- β in Cardiac Fibroblasts and Cardiac Myocytes: a Potential Role in Heart Fibrosis
TL;DR: It is proposed that CTGF is an important mediator of TGF- beta signaling in the heart and abnormal expression of this gene could be used as a diagnostic marker for cardiac fibrosis.
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Subtle acquired renal injury as a mechanism of salt-sensitive hypertension.
TL;DR: This review provides an explanation of how initially subtle renal injury promotes a tendency toward hypertension, and how decreasing salt intake ameliorates the hypertension.