What is the meaning of L in L glutathione?
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35 Citations | Thus, L-2-oxothiazolidine-4-carboxylate increased tissue glutathione concentrations and stimulated growth in rats. |
| Taken together, these methods allowed determination of glutathione concentration and fractional synthesis rate in red blood cells using L-[(15)N] glutamic acid infusion. | |
32 Citations | The observed protonation of adsorbed l-glutathione upon interaction with proline goes along with a structural change of the former, which seems to play an important role for enantiodiscrimination. |
183 Citations | The primary mechanism may be through L-cysteine as a cellular source for glutathione production. |
51 Citations | The remaining 35% of the specific L-[3H]glutamate binding may be due to a second class of glutamate binding sites which is insensitive to glutathione. |
| The novel use of L-γ-glutamyl-L-cysteinyl-[2-13C]glycine allowed the intra- and extracellular glutathione pools to be distinguished unequivocally, enabling the direct and non-invasive observation over time of the glutathione redox status in both compartments. | |
| Depending on the protonation state during adsorption of l-glutathione, the response toward identical protonation-deprotonation stimuli is significantly different. |
Related Questions
What are benefits of glutathione?5 answersGlutathione (GSH) offers various benefits due to its role as an antioxidant and immune system modulator. It aids in protecting cells from oxidative stress caused by reactive oxygen species and free radicals. GSH plays a crucial role in maintaining redox balance, regulating inflammation, and enhancing immune responses against infections like tuberculosis. Additionally, GSH supplementation can help replenish depleted levels, potentially benefiting individuals with diseases linked to oxidative stress, such as cardiovascular disorders and neurodegenerative conditions. Moreover, GSH has been highlighted as a key player in combating inflammatory diseases and infections like COVID-19, emphasizing its significance in maintaining overall health and well-being.
What are the main uses of glutathione and L-glutathione?4 answersGlutathione, a tripeptide composed of glutamate, cysteine, and glycine, has several important uses. It acts as an antioxidant, protecting cells against oxidative stress. Glutathione also plays a role in detoxification, immune system modulation, and regulation of cellular processes such as proliferation and apoptosis. Additionally, it is involved in energy utilization, cleansing of cells, and elimination of toxins. Glutathione is known as the "cellular redox buffer" and is involved in various physiological functions beyond redox homeostasis, such as enzymatic conversions, protein folding, iron sensing, and biosynthesis of various compounds. L-glutathione, being the same as glutathione, can be used interchangeably with the same functions and roles. Therefore, the main uses of both glutathione and L-glutathione include antioxidant activity, detoxification, immune modulation, regulation of cellular processes, and involvement in various physiological functions.
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