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What specific types of mutations have been observed in salmonid populations under stressful conditions? 


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Salmonid populations under stressful conditions exhibit various types of mutations. Studies on Dolly Varden charr in Kamchatka show stress-induced phenotype transformations without a common vector. Research on Escherichia coli and Salmonella highlights stress-induced mutagenesis, increasing beneficial mutations under selective pressures. In aquaculture, bacterial pathogens like Edwardsiella piscicida and Vibrio harveyi develop significant single-nucleotide polymorphisms (SNPs) and mutations in response to stressors. Daphnia pulex exposed to environmental stressors display accelerated rates of deletions and duplications, particularly under metal exposure, impacting mutational load. Stress conditions can enhance mutation rates in salmonid populations, leading to diverse genetic changes such as SNPs, deletions, and duplications, influencing their adaptive responses to environmental challenges.

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Not addressed in the paper.
Open accessJournal ArticleDOI
Ashley B. Williams, Patricia L. Foster 
12 Mar 2012
28 Citations
Stress-induced mutagenesis in salmonid populations can lead to beneficial mutations by modulating genetic change, enhancing adaptability under challenging conditions.
Mutations leading to morphological changes like increased pectoral fin rays and altered skull shapes have been observed in salmonid populations under stressful conditions, possibly due to gene drift and founder effects.
The study observed significant single-nucleotide polymorphisms (SNPs) and mutations in genes related to flagella, fimbriae, and membranes in Edwardsiella piscicida and Vibrio harveyi under stressed environments.
Not addressed in the paper.

Related Questions

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What are the different types of mutations?5 answersDifferent types of mutations include single base-pair substitutions in coding, regulatory, and splicing-relevant regions of genes. Other types of pathogenic mutations are micro-deletions, micro-insertions, duplications, repeat expansions, combined micro-insertions/deletions (indels), inversions, gross deletions, insertions, and complex rearrangements. Mutations can occur not only in coding sequences but also in promoter regions, splice junctions, introns, untranslated regions, and noncoding RNAs. Mutations can vary in size, from structural variants to single base-pair substitutions. Mutations can be classified into gene mutations, which involve single genes, and chromosomal mutations, which involve chromosomal segments or whole chromosomes. Gene mutations contribute to inherited diseases, while chromosomal mutations can lead to inherited diseases or acquired diseases. Exposure to physical or chemical mutagens can increase the incidence of inherited gene and chromosomal mutations. Mutations in somatic cells can also occur and are implicated in the development of human cancers.
How recombinant DNA technology enhance resistance to environmental stress in agriculture?4 answersRecombinant DNA technology has been used to enhance resistance to environmental stress in agriculture. This technology allows for the insertion of specific traits into the plant genome, resulting in genetically modified crops with improved tolerance to abiotic and biotic stresses. Through genetic engineering, potential genes, transcription factors, and miRNAs involved in stress response processes can be identified and manipulated to enhance plant resilience and production. The use of CRISPR/Cas gene-editing technique has also gained popularity in creating stress-tolerant plant variants. Recombinant DNA technology enables faster and more accurate insertion of desired traits compared to traditional breeding methods. By genetically modifying both nuclear and plastid plant genomes, transgenic plants with distinct characteristics, such as enhanced yield, nutritional quality, and biotic and abiotic tolerance, can be developed. Transgenic approaches can manipulate key genes in both host plants and pathogens to confer effective resistance against diseases. Overall, recombinant DNA technology offers promising applications for enhancing resistance to environmental stress in agriculture.
How SNPs help aquaculture molecular breeding?3 answersSNPs (single nucleotide polymorphisms) play a crucial role in aquaculture molecular breeding. They offer a cost-effective solution for identifying superior individuals from the wild, which can be recruited into breeding programs. SNPs are used as genetic markers for various applications such as high-density genetic linkage map construction, quantitative trait loci (QTL) mapping, genome-wide association study (GWAS), and genomic selection (GS). Genotype imputation, a strategy that predicts ungenotyped SNPs using a reference population genotyped at a high-density, can reduce genotyping costs and facilitate the broader uptake of genomic selection in aquaculture breeding programs. Additionally, the emergence of low-cost whole-genome sequencing platforms and the availability of genomic data have contributed to a significant reduction in the cost of marker development, improving precision and accuracy in aquaculture breeding programs. SNP genotyping methods, such as AmpliSeq target sequencing, have been developed to accelerate the application of marker-assisted selection (MAS) and genomic selection (GS) in aquaculture breeding programs.
How can SNPs be used in aquaculture molecular breeding?5 answersSNPs can be used in aquaculture molecular breeding in several ways. Firstly, genotype imputation can be used to predict ungenotyped SNPs in populations genotyped at a low-density, using a reference population genotyped at a high-density. This strategy can reduce genotyping costs and facilitate the broader uptake of genomic selection in aquaculture breeding programs. Secondly, SNPs can be used to construct high-density linkage maps, which can help in identifying markers associated with important economic traits and unraveling quantitative trait loci (QTL). These markers can then be incorporated into breeding programs to accelerate genetic gains. Thirdly, SNPs can be used in marker-assisted selection and the linkage of quantitative traits to genomic loci, allowing for effective management of broodstock and the selection of superior individuals. Finally, SNPs can be used in genomic selection, where a subset of markers selected by genome-wide association studies (GWAS) can be used to improve the prediction accuracy of GS while reducing genotyping costs.
What is the difference between SNPs and mutations?4 answersSingle nucleotide polymorphisms (SNPs) and mutations are both forms of genetic variation, but they have some key differences. SNPs are single nucleotide changes in the DNA sequence that occur commonly in the human genome. They are the most common type of genetic variation and account for more than 90% of all human genetic variations. SNPs can be used to study the genetic basis of common diseases, complex traits, and human population ancestry. On the other hand, mutations are irreversible sequence variations in the DNA that can occur spontaneously or non-spontaneously. Mutations can encompass various types of variations in the genome and can lead to the acquisition of cancer hallmarks in the cell transformation process. While SNPs are a type of genetic polymorphism, mutations can have a broader impact on phenotypes and disease development.

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