Why the TVL- GAS strand is more affected in terms of vision irregularities?
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The TVL-GAS strand is more affected in terms of vision irregularities due to various factors. Gas exposure during disasters like the 1984 Union Carbide gas leak in Bhopal can lead to ocular issues such as vision difficulties, watering, and cataracts . Additionally, exposure to gas discharge lamps can cause asthenopic complaints, affecting visual concentration and acuity, especially in young women with autonomic lability . Furthermore, the biological function of lncRNA GAS5 plays a role in regulating retinal ganglion cell survival and differentiation, with down-regulation of GAS5 promoting cell proliferation and differentiation while reducing apoptosis . These combined factors contribute to the increased susceptibility of the TVL-GAS strand to vision irregularities.
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| Papers (5) | Insight |
|---|---|
15 Citations | The TVL-GAS strand is more affected due to lncRNA GAS5 down-regulation, promoting retinal ganglion cell survival in glaucoma by activating the TGF-β pathway, enhancing proliferation and differentiation. |
Open access•Journal Article 2 Citations | The TVL-GAS strand is more affected due to high visual demands under gas discharge lamp illumination, impacting predominantly young women with autonomic lability and various visual impairments. |
| The TVL-GAS strand is more affected due to a higher prevalence of pinguecula, cataracts, and vision difficulties among Bhopal gas disaster survivors, emphasizing the need for vision care in this population. | |
| Not addressed in the paper. | |
10 Citations | Excess oxygen injection during gas myelography led to increased CSF pressure, causing retinal hemorrhages and vision loss in the TVL-GAS strand due to secondary venous stasis. |
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