Showing papers on "Alveolar hydatid disease published in 2007"
TL;DR: The treatment of Alveolar Hydatid Disease is curative radical resection, and pre-operative imaging studies to determine the extent and stage of the disease are of crucial importance.
Abstract: Purpose : We report six cases of Alveolar Hydatid Disease (five in the liver and one in the gastrosplenic ligament invading the spleen) in which curative resection of the liver (five cases) and splenectomy (one case) were performed. Material and Methods: The records of the six patients with AHD were retrospectively evaluated. Demographics of the patients, symptoms, laboratory findings, including serology were recorded. Imaging studies determined the extent of the disease preoperatively. Classification of the lesions was done according to the PNM (P = parasitic mass in the liver, N = involvement of neighbouring organs, and M = metastasis) staging system designed by the World Health Organization. All the surgical procedures were performed as complete resections, where negative margins were approved by frozen sections. Chemotherapy with albendazole (10 mg/kg/day) was continued postoperatively for two years in five of the six patients who were alive. Results : All of the cases were from East Anatolia of Turkey, which is an endemic region. The mean age was 39.6 years (15-54 years). Major complications occurred post-operatively in all patients, possibly due to the extensive resection. No recurrence was seen during the 5 year follow-up of two cases and 2 year follow-up of three cases. Conclusion: The treatment of Alveolar Hydatid Disease is curative radical resection. Thus, pre-operative imaging studies to determine the extent and stage of the disease are of crucial importance.
16 citations
TL;DR: Multiple lobulated lesions located between two segments of the lung and of varying shape appear to be characteristic of pulmonary alveolar hydatid disease caused by E.
Abstract: Alveolar hydatid disease is a highly malignant form of echinococcosis caused by the larvae of the cestode Echinococcus multilocularis Alveolar hydatid disease always affects the liver and can metastasise to the lungs and brain The case reports describe the radiological features of alveolar hydatid disease of the lung caused by E multilocularis Multiple nodules which varied in size and shape were seen on CXR, CT showed most nodules to be lobulated, well circumscribed and of varying shape Multiple lobulated lesions located between two segments of the lung and of varying shape appear to be characteristic of pulmonary alveolar hydatid disease caused by E multilocularis
10 citations
TL;DR: Alveolar hydatid disease of the liver is rare in dogs, and should be envisaged as a possible differential diagnosis in cases of space-occupying processes in the liver, even in young animals, as the incubation period of this disease in the dog can be considerably shorter than in humans.
Abstract: A 2-years old male Labrador retriever dog was presented with intermittent therapy-resistant diarrhoea, accompanied by vomiting, inappetence, apathy, and mild fever. The blood analysis showed an anaemia, neutrophilia, eosinophilia, and increased liver enzymes. Abdominal palpation was slightly painful. X-rays and echography revealed a severely enlarged liver with multiple cavernous structures. Histopathologic examination of liver biopsies showed a severe chronic granulomatous hepatitis with numerous parasitic cysts. Morphology of the cysts was compatible with the metacestode stage of Echinococcus multilocularis. The dog was only 2-years old at the time of diagnosis. Although alveolar hydatid disease of the liver is rare in dogs, it should be envisaged as a possible differential diagnosis in cases of space-occupying processes in the liver, even in young animals, as the incubation period of this disease in the dog can be considerably shorter than in humans.
10 citations
Journal Article•
TL;DR: Alvelolar hydatid disease is caused by E. multilocularis and is studied in a 50 year old woman who presented with a hepatic mass and 5 year follow up of the patient was satisfactory without any complaint.
Abstract: Alvelolar hydatid disease is caused by E. multilocularis. Human infection occurs at the larval stage of this small tape worm (1.2 to 4.5 mm). In this article we studied alveolar hydatid disease in a 50 year old woman who presented with a hepatic mass. Liver biopsy and histopathologic evaluation showed alvelolar hydatidosis of the liver. Then resection of the left lobe of liver was done, with medical treatment with oral Albendazole (15 mg/kg/12h) for 6 weeks with 2 week intervals. The drug was continued for 4 courses. 5 year follow up of the patient was satisfactory without any complaint.
9 citations
TL;DR: The purpose of this study is to show the spectrum of adjacent organ invasion and to make a brief review of hepatic alveolar hydatid disease, using CT and MR imaging of three patients with various adjacent organ invasions surgically and histologically proven to be AHD.
Abstract: The purpose of this study is to show the spectrum of adjacent organ invasion and to make a brief review of hepatic alveolar hydatid disease (AHD), using CT and MR imaging. We retrospectively reviewed CT and MR images of three patients with various adjacent organ invasions surgically and histologically proven to be AHD. Local invasion to right kidney and adrenal, right hemidiaphragm and lung were detected in one patient, right adrenal in another patient and gall bladder, duodenum, gastric wall and pancreas invasion in the other. AHD may rarely extend to the gall bladder, stomach, duodenum, pancreas, right adrenal and kidney, diaphragm, pleura and lung. The extension of the disease outside the liver is usually encountered in patients with large, peripherally located masses in the advanced stage of the disease.
5 citations
Patent•
29 Nov 2007
TL;DR: In this paper, a recombined Em18R2 antigen, obtained by removing a C-terminal part from an echinococcus alveolar hydatid Em18 antigen, is brought to react with a subject's serum.
Abstract: PROBLEM TO BE SOLVED: To provide an inspecting method which is very useful for simply and quickly diagnosing echinococcus alveolar hydatid disease, and has high specificity, in comparison with conventional methods. SOLUTION: In the method for diagnosing the echinococcus alveolar hydatid disease, a recombined Em18R2 antigen, obtained by removing a C-terminal part from an echinococcus alveolar hydatid Em18 antigen, is brought to react with a subject's serum. This recombined Em18R2 antigen is immobilized on a support and brought to react with the subject's serum, and then a labeled probe is brought to react with it, and its label is detected. This inspection method has the high specificity, in comparison with conventional methods and is very useful for simply and quickly diagnosing the echinococcus alveolar hydatid disease, by combining it with another simple inspecting method. COPYRIGHT: (C)2008,JPO&INPIT
3 citations
TL;DR: This patient from rural India was diagnosed to have hydatid cyst disease, on the basis of CT image morphology and a positive immunoblot test (95% specific).
Abstract: The diagnosis of hydatid cyst disease was made for the case presented in the December 2006 Aperture based on this computed tomography (CT) scan of the abdomen. The CT shows the presence of two large hydatid cysts, along with daughter cysts, in the right lobe of the liver.
Hydatid disease is caused by the Echinococcus species, of which E. granulosis (cystic hydatid disease) and E. multilocularis (alveolar hydatid disease) are the most important. E. vogeli and E. oligarthus, both of which cause polycystic hydatid disease, are rare and are seen primarily in Central and South America.
This patient from rural India was diagnosed to have hydatid cyst disease, on the basis of CT image morphology and a positive immunoblot test (95% specific). He is currently being treated conservatively with Albendazole.
1 citations