Showing papers on "Curcuma amada published in 2010"
TL;DR: The chloroform extract of mango ginger rhizome was subjected to antibacterial activity-guided purification by repeated silica gel column chromatography to obtain a pure compound, and the structure of the isolated compound was deduced by analysing UV, IR, LC-MS and 2D-HMQCT NMR spectral data, and named it as amadaldehyde, a novel compound.
Abstract: Mango ginger (Curcuma amada Roxb.) rhizome is used in the manufacture of pickles and other food preparations due to its unique raw mango flavour. The chloroform extract of mango ginger rhizome was subjected to antibacterial activity-guided purification by repeated silica gel column chromatography to obtain a pure compound. The structure of the isolated compound was deduced by analysing UV, IR, LC-MS and 2D-HMQCT NMR spectral data, and named it as amadaldehyde, a novel compound. It exhibited a wide range of antibacterial activity with potential bactericidal activity against several bacteria. The purified compound also exhibited antioxidant activity, cytotoxicity and platelet aggregation inhibitory activities.
66 citations
TL;DR: The first report on isolation and antimycobacterial activity of this dialdehyde from C. amada is reported, which exhibited antitubercular activity against Mycobacterium tuberculosis H(37)Rv strain in BACTEC-460 assay.
62 citations
TL;DR: In this paper, the authors investigated the phenol content and antioxidant activity of a non-conventional Curcuma sp. caesia in comparison with another species, C. amada, and found that the total phenol contents of the methanolic rhizome extracts of both species were 37.64 and 44.33 mg Tannic acid equivalents (TAE)/g dry material.
Abstract: The present study aimed to investigate the phenol content and antioxidant activity of a non-conventional Curcuma sp. namely, Curcuma caesia in comparison with another species, Curcuma amada. The total phenol contents of the methanolic rhizome extracts of C. amada and C. caesia were 37.64 and 44.33 mg Tannic acid equivalents (TAE)/g dry material, respectively. The reducing power, and superoxide, ABTS and DPPH radical scavenging activities of C. caesia were higher than C. amada. These results supported that the non-conventional C. caesia could be an economically important plant species due to its antioxidant potential.
18 citations
TL;DR: The concurrent use of the different types of molecular markers valuable to comprehend a dependable variability pattern in the germplasm assayed found to cover diverse part of the genome together with neutral and functional regions.
17 citations
01 Jan 2010
TL;DR: Curcuma amada has a long history of traditional use as a medicinal plant among the indigenous Monsang tribe of Manipur and its rhizome has been used in treating various local ailments.
Abstract: Summary Curcuma amada has a long history of traditional use as a medicinal plant among the indigenous Monsang tribe of Manipur. Its rhizome has been used in treating various local ailments. The hypoglycemic and antihyperglycemic activity of the crude aqueous methanolic (1:4) extract of Curcuma amada was evaluated in normal and alloxaninduced diabet ic mice. Administration of different doses (150�650 mg/kg b.w.) lowered blood glucose level in a doseand timedependent manner. Mild hypoglycemic activity was observed with all the administered doses, while the antihyperglycemic activity was found to be pronoun ced above the dose of 250 mg/kg b.w. No apparent toxicity was observed in any of the mice even at the dose of 650 mg/kg b.w. Glucose tolerance was also improved in both normal and diabetic mice on administration of the extract. The results were compared with those of insulin, glibenclamide and metformin which were used as reference drugs.
9 citations
02 Sep 2010
1 citations