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Showing papers on "Fagonia cretica published in 2015"


Journal ArticleDOI
19 Feb 2015
TL;DR: The other effects of Fagonia species include anti-inflammatory, analgesic, antipyretic and thrombolytic activities are observed.
Abstract: Desert plants are unique adaptation from environmental conditions. Fagonia is a genus of plant in the family zygophyllaceae with about 20 species around Mediterranean to India, S. Africa, California, Chili. The local name of fagonia is dhamasa. They are traditionally well known for the treatment of hemorrhoids, inflammation, sores, leprosy, open wounds and fever in the form of internal and external conventional formulation. When the powder that is made up of the whole plant of F. schweinfurthii is dusted on boils and skin eruptions, it causes healing, when the whole plant is boiled in water, its bath is useful for allergies and other skin diseases and decoction is given orally as blood purifier. The other species like Fagonia bruguieri its aqueous extract is claimed for anti-allergy. Methanolic extract of Fagonia cretica is claimed for good antimicrobial potential and it exhibited strong free radical scavenging properties against reactive oxygen and nitrogen species . The other effects of Fagonia species include anti-inflammatory, analgesic, antipyretic and thrombolytic activities are observed. Many chemical constituent's, such as triterpenoids, saponins, flavonoid glycosides, etc., have already been reported in different Fagonia spp.

11 citations



Journal Article
TL;DR: The methanolic and water extracts of F. cretica L. at oral dose of (400 mg/kg) showed highly significant (p<0.01) hepatoprotective effect and histopathological examinations of liver sections comparable with the standard hepatoprotsective drug Silymarin which served as a positive control.
Abstract: Fagonia cretica L. (Zygophyllaceae) herb is widely distributed in Sudan and used in Sudanese traditional medicine for the treatment of various disorders. The present study was designed to assess the hepatoprotective activity and cytotoxicity of methanolic and water extracts of F. cretica L. These extracts were studied for their hepatoprotective activity using CCl4 induced liver damage in wistar albino rats. The methanolic and water extracts of F. cretica L. at oral dose of (400 mg/kg) showed highly significant (p<0.01) hepatoprotective effect. These biochemical observations wereconfirmed by histopathological examinations of liver sections comparable with the standard hepatoprotective drug Silymarin (100 mg/kg) which served as a positive control.

3 citations


27 Jun 2015
TL;DR: In this paper, the antimicrobial potential and phytochemical profile of Eremostachys laciniata plant was evaluated to look into possible natural therapy agents, which revealed that Fagonia cretica have an excellent anti-bacterial activity and can be used for disease therapy.
Abstract: The aim of the present research was to evaluate the antimicrobial potential and phytochemical profile of Eremostachys laciniata plant to look into possible natural therapy agents. The shade-dried whole plant material of Eremostachys laciniata was soaked in methanol for 10 days. The powdered drug was extracted with 80 % methanol three times and filtered at room temperature. The filtrate was evaporated in rotary to get a dark-greenish residue (extract), which was further suspended in water and partitioned successively with n-hexane, chloroform, distill water and n-butanol to obtain nhexane- soluble, chloroform-soluble, distill water-soluble, n-butanol soluble and aqueous fractions, respectively. Different fractions (chloroform, n-hexane, butanol, water and ethyl acetate) of the plant were tested against various bacterial strains namely E.coli, S.aureus, S.typheae, P.auriginosa.The extracted fractions of the plant exhibit moderate activities showing 9mm to 18mm inhibition against different strains of bacteria as compared to the control, which gave maximum inhibition upto 29mm. The Eremostachys laciniata was found to be good source of alkaloids, flavonoids, tennins, resins, carbohydrate, starch, proteins, glycosides, coumarin, terponides, steroids and saponine. Anthranol glycosides were absent in the plant. The above results revealed that Fagonia cretica have an excellent anti-bacterial activity and can be used for disease therapy.

1 citations


Journal Article
TL;DR: Fagonia cretica L belongs to Zygophyllaceae and has very important and significant Phytocemicals The entire plant was shade dried, and the powder was subjected to hydrodistillation to get essential oils Later the oils were chemically analysed It showed compounds among which 20 are identified and 23 are yet to be identified as discussed by the authors.
Abstract: Fagonia cretica Lbelongs to Zygophyllaceae is having very important and significant Phytocemicals The entire plant of Fagonia cretica Lwas shade dried, and the powder was subjected to hydrodistillation to get essential oils Later the oils were chemically analysed It showed compounds among which 20 are identified and 23 are yet to be identified Some dried powder was extracted with different polar and non polar solvents by using Soxhelt apparatus The extracts thus obtained were tested for their antimicrobial activity by using disc diffusion and cup plate methods against various pathogens The methanol extract showed prominent antimicrobial activity