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Showing papers on "Major Salivary Gland published in 1983"


Journal ArticleDOI
TL;DR: The diagnosis of mycobacterial infections of the major salivary glands, compared to cervical lymph nodes, is equally — if not more — difficult to make.
Abstract: Mycobacterium tuberculosis and atypical mycobacterium are well-known causes of cervical lymphadenopathy, most often presenting without symptoms of systemic infection. These organisms may also directly involve the parenchyma of the major salivary glands and their periglandular or intraglandular nodes. The diagnosis of mycobacterial infections of the major salivary glands, compared to cervical lymph nodes, is equally--if not more--difficult to make. The differential must include the same spectrum of inflammatory and neoplastic diseases as well as lesions unique to the salivary glands. Selected cases are presented and discussed to show that principles established for the treatment of cervical mycobacterial infections must also be applied to major salivary gland infections. In particular, cutaneous fistulas may result from incisional biopsy or incision and drainage of the involved gland. Partial parotidectomy or submaxillary gland excision may be required, followed by multidrug, antituberculous chemotherapy for one to two years. Culturing of the organisms is extremely difficult, and the diagnosis of either mycobacterium tuberculosis or atypical mycobacterial infection must be based on a combination of history and clinical examination, skin testing, histopathology, acid-fast stains, culture, and response to surgery and antituberculous chemotherapy.

60 citations


Journal ArticleDOI
TL;DR: Clarified and dialyzed mixed saliva-water rinses, obtained from patients receiving radiation treatment of the major salivary glands, exhibited quantitative reductions in total protein content and qualitative changes in protein composition.
Abstract: Clarified and dialyzed mixed saliva-water rinses, obtained from patients receiving radiation treatment of the major salivary glands, exhibited quantitative reductions in total protein content and qualitative changes in protein composition. Radiation or post-radiation saliva preparations supported enhanced growth of Streptococcus mutans, but reduced growth of Streptococcus sanguis relative to growth on pretreatment saliva.

35 citations


Journal ArticleDOI
TL;DR: Parasympathetic decentralization but not sympathetic denervation caused the sublingual glands to develop a super-sensitivity to substance P, and the secretory effect of substance P was not exerted via cholinergic, alpha- adrenergic or beta-adrenergic receptors.

30 citations


Journal ArticleDOI
TL;DR: Salivary gland imaging with sodium pertechnetate Tc 99m showed absence of all major salivary glands, and a radionuclide dacryocystogram demonstrated decreased lacrimal secretion on the left side.
Abstract: • A 12-year-old boy had dry mouth and teeth in poor condition. Salivary gland imaging with sodium pertechnetate Tc 99m showed absence of all major salivary glands, and a radionuclide dacryocystogram demonstrated decreased lacrimal secretion on the left side. No evidence of abnormal inheritance could be demonstrated. (Arch Otolaryngol1983;109:197-198)

28 citations


Journal ArticleDOI
TL;DR: The true frequency of primary squamous cell carcinomas of the major salivary glands is less than 1% of all tumors in the parotid gland and approximately 4% for the submandibular gland.
Abstract: Primary squamous cell carcinomas of the major (parotid and submandibular) salivary glands are uncommon neoplasms. Statistics contrary to that statement are tainted by the inclusion of mucoepidermoid carcinomas and, in the instance of the parotid gland, by metastatic carcinomas. The true frequency is less than 1% of all tumors in the parotid gland and approximately 4% for the submandibular gland.

21 citations


Journal ArticleDOI
TL;DR: An adenoid cystic carcinoma (cylindroma) of the submandibular salivary gland presented 17 years after diagnosis with a compressive syndrome of the spinal cord as well as a local recurrence, the first reported case of such an occurrence.

10 citations


Journal ArticleDOI
TL;DR: Parotid origin dominates the statistics concerning site of origin and there is no relationship of the carcinoma to systemic rheumatic disease or Sjögren's syndrome.
Abstract: Carcinoma ex lymphoepithelial lesion is a poorly differentiated, nonkeratinizing carcinoma presumably arising from the epimyoepithelial islands of the lymphoepithelial lesion of the major salivary glands. Parotid origin dominates the statistics concerning site of origin. There is no relationship of the carcinoma to systemic rheumatic disease or Sjogren's syndrome.

7 citations


Journal ArticleDOI
Yngve Östberg1
TL;DR: In 19 patients with the microscopical diagnosis of lympho-epithelial lesion, 84% fulfilled all criteria of Sjogren's syndrome and the disease in the 2 patients with M-component took a malignant course, culminating in immunoblastic sarcoma and myelomatosis.
Abstract: The histopathological diagnosis 'benign lympho-epithelial lesion' characterizes the major salivary gland disease in Sjogren's syndrome. It is not known if all cases with microscopically diagnosed benign lympho-epithelial lesion are variants of Sjogren's syndrome. The present clinical investigation showed that in 19 patients with the microscopical diagnosis of lympho-epithelial lesion, 84% fulfilled all criteria of Sjogren's syndrome. The rheumatoid factor and/or antinuclear factor was found in 84% and M-component was present in 16%. Sialography revealed sialectasis in all parotid glands. Salivary gland enlargement was found in 79%, and keratoconjunctivitis sicca in 89% of the patients. Systemic disease was found in 32%. The disease in the 2 patients with M-component took a malignant course, culminating in immunoblastic sarcoma and myelomatosis. The clinical diagnosis 'autoimmune sialadenitis' is proposed for the oral and salivary gland component is Sjogren's syndrome.

7 citations


Journal ArticleDOI
TL;DR: Bioassay data support the hypothesis that salivary glands participate in endocrine regulation of the development and maintenance of connective tissues and suggest endocrine function of the salivARY glands and possible interactions between the pancreatic islets and salIVary glands.

3 citations