Showing papers on "Pulmonary diffusion published in 1967"

Vitamin B12 Absorption by Inhalation

Abstract: SUMMARY Cyanocobalamin in the form of an aerosol was inhaled by normal subjects, patients with pulmonary diffusion defects and patients with vitamin B12 deficiency. In all groups there was a rapid increase in serum B12 levels suggesting that absorption had occurred by diffusion through the lung alveoli. Six patients with pernicious anaemia given daily inhalations showed complete clinical and haematological remission and a group of six patients with B 2 deficiency were maintained in remission for 12 months. While effective, this method of administration of vitamin B12 is not regarded as superior to that of injections and is therefore considered to have no therapeutic application. The possibility of inducing pulmonary damage is considered.