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A. Graham Calder
Researcher at Rowett Research Institute
Publications - 14
Citations - 1905
A. Graham Calder is an academic researcher from Rowett Research Institute. The author has contributed to research in topics: Fermentation & Methionine. The author has an hindex of 12, co-authored 14 publications receiving 1645 citations. Previous affiliations of A. Graham Calder include University of Aberdeen & University of Southern Denmark.
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Journal ArticleDOI
Two Routes of Metabolic Cross-Feeding between Bifidobacterium adolescentis and Butyrate-Producing Anaerobes from the Human Gut
Álvaro Belenguer,Sylvia H. Duncan,A. Graham Calder,Grietje Holtrop,Petra Louis,Gerald Lobley,Harry J. Flint +6 more
TL;DR: It is concluded that two distinct mechanisms of metabolic cross- feeding between B. adolescentis and butyrate-forming bacteria may operate in gut ecosystems, one due to consumption of fermentation end products (lactate and acetate) and the other due to cross-feeding of partial breakdown products from complex substrates.
Journal ArticleDOI
Contribution of acetate to butyrate formation by human faecal bacteria.
Sylvia H. Duncan,Grietje Holtrop,Gerald Lobley,A. Graham Calder,Colin S. Stewart,Harry J. Flint +5 more
TL;DR: Different carbohydrate-derived energy sources affected butyrate formation by mixed human faecal bacteria growing in continuous or batch cultures, consistent with a major role for bacteria related to F. prausnitzii and Roseburia spp.
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Identification of the NH2‐terminal blocking group of calcineurin B as myristic acid
Alastair Aitken,Philip Cohen,Sitthivet Santikarn,Dudley H. Williams,A. Graham Calder,A Smith,Claude B. Klee +6 more
TL;DR: The NH2‐terminal blocking group of the Ca 2+‐binding B‐subunit of calcineurin (protein phosphatase‐2B) has been identified as myristic acid by fast atom bombardment mass spectrometry and gas chromatography and may facilitate the identification of other proteins with this blocking group.
Journal ArticleDOI
Major phenylpropanoid‐derived metabolites in the human gut can arise from microbial fermentation of protein
Wendy R. Russell,Sylvia H. Duncan,Lorraine Scobbie,Gary Duncan,Louise Cantlay,A. Graham Calder,Susan E. Anderson,Harry J. Flint +7 more
TL;DR: This study demonstrates that certain microbial species have the ability to ferment all three AAAs and that protein fermentation is the likely source of major phenylpropanoid-derived metabolites in the colon.
Journal ArticleDOI
Oxidation of essential amino acids by the ovine gastrointestinal tract.
Gerald Lobley,Xiangzhen Shen,Guowei Le,David Bremner,Eric Milne,A. Graham Calder,Susan E. Anderson,Ngaire Dennison +7 more
TL;DR: Differences in PDV: MDV net appearance ratios probably reflect incomplete re-absorption of endogenous secretions and, together with the varied oxidative losses measured, will alter the pattern of AA net supply to the rest of the animal.